Evidence map›Paper›PMID 27841697›Full record

ArticleCell cycle (Georgetown, Tex.)2017

Translational control of gurken mRNA in Drosophila development.

Christopher J Derrick, Timothy T Weil

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Finishing the egg.Genetics · 2024
    Article
  2. Review
  3. Article
  4. Review
  5. Auto-regulatory feedback by RNA-binding proteins.Journal of molecular cell biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher J Derricka Department of Zoology , University of Cambridge , Cambridge , UK.
Timothy T Weila Department of Zoology , University of Cambridge , Cambridge , UK.
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Localized mRNA translation is a widespread mechanism for targeting protein synthesis, important for cell fate, motility and pathogenesis. In Drosophila, the spatiotemporal control of gurken/TGF-α mRNA translation is required for establishing the embryonic body axes. A number of recent studies have highlighted key aspects of the mechanism of gurken mRNA translational control at the dorsoanterior corner of the mid-stage oocyte. Orb/CPEB and Wispy/GLD-2 are required for polyadenylation of gurken mRNA, but unlocalized gurken mRNA in the oocyte is not fully polyadenylated.

Indexed as

Embryonic DevelopmentAnimalsDrosophila melanogasterDrosophila ProteinsModels, BiologicalOocytesPhosphorylationProtein BiosynthesisProtein KinasesRNA-Binding ProteinsRNA, MessengerTransforming Growth Factor alphaDrosophila Proteinsgrk protein, Drosophilaorb protein, DrosophilaProtein KinasesRNA-Binding ProteinsRNA, MessengerTransforming Growth Factor alphaDrosophilagurkenoogenesisprocessing bodiestranslation

Identifiers

PMID27841697
PMCPMC5270528
OpenAlexW2949562067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.