Evidence map›Paper›PMID 27841420›Full record

ReviewChemical Society reviews2017

Photonic crystals: emerging biosensors and their promise for point-of-care applications.

Hakan Inan, Muhammet Poyraz, Fatih Inci, Mark A Lifson, Murat Baday, Brian T Cunningham, Utkan Demirci

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Article
  2. Materials and System Design for Self-Decision Bioelectronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Enzyme-containing-hydrogel/TiOScientific reports · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Optical Sensors for Bacterial Detection.Sensors (Basel, Switzerland) · 2023
    Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hakan InanDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, 3155 Porter Drive, Palo Alto, CA 94304, USA. utkan@stanford.edu.
Muhammet PoyrazDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, 3155 Porter Drive, Palo Alto, CA 94304, USA. utkan@stanford.edu and Department of Electrical Engineering, Stanford University, Stanford, CA, USA.
Fatih InciDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, 3155 Porter Drive, Palo Alto, CA 94304, USA. utkan@stanford.edu.
Mark A LifsonDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, 3155 Porter Drive, Palo Alto, CA 94304, USA. utkan@stanford.edu.
Murat BadayDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, 3155 Porter Drive, Palo Alto, CA 94304, USA. utkan@stanford.edu.
Brian T CunninghamDepartment of Electrical and Computer Engineering, Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA. bcunning@illinois.edu.
Utkan DemirciDemirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Department of Radiology, Canary Center at Stanford for Cancer Early Detection, 3155 Porter Drive, Palo Alto, CA 94304, USA. utkan@stanford.edu and Department of Electrical Engineering (by courtesy), Stanford University, Stanford, CA, USA.

Funding

Point-of-Care Rapid Blood Testing Using Microfluidic DevicesR01AI081534 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMIRCI, UTKAN · 2009 to 2013
$2.1M
Platform technology for detection of cancer-associated viruses in HIV patientsR01DE024971 · NIDCR · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN, KAYE, KENNETH M · 2015 to 2019
$2.1M
Novel disposable microchips for HIV-1 viral loadR01AI093282 · NIAID · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN · 2012 to 2015
$1.7M
Rapid Disease Diagnostics using Photonic Crystal Enhanced Antigen BiomarkerR01GM108584 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ANDERSON, KAREN SUE, CUNNINGHAM, BRIAN T. · 2014 to 2017
$1.6M
Portable Nanostructured Photonic Crystal Device for HIV-1 Viral LoadR01AI120683 · NIAID · STANFORD UNIVERSITY · PI CUNNINGHAM, BRIAN T., DEMIRCI, UTKAN · 2016 to 2019
$1.5M
Photonic Crystal Enhanced Fluorescence: Development of Sensors Structures and DetR33CA177446 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CUNNINGHAM, BRIAN T., ZANGAR, RICHARD C · 2013 to 2015
$712k
NCI NIH HHS R33 CA177446NIAID NIH HHS R01 AI081534NIAID NIH HHS R01 AI093282NIAID NIH HHS R01 AI120683NIDCR NIH HHS R01 DE024971NIGMS NIH HHS R01 GM108584
6 · The paper itself

Abstract

Biosensors are extensively employed for diagnosing a broad array of diseases and disorders in clinical settings worldwide. The implementation of biosensors at the point-of-care (POC), such as at primary clinics or the bedside, faces impediments because they may require highly trained personnel, have long assay times, large sizes, and high instrumental cost. Thus, there exists a need to develop inexpensive, reliable, user-friendly, and compact biosensing systems at the POC. Biosensors incorporated with photonic crystal (PC) structures hold promise to address many of the aforementioned challenges facing the development of new POC diagnostics. Currently, PC-based biosensors have been employed for detecting a variety of biotargets, such as cells, pathogens, proteins, antibodies, and nucleic acids, with high efficiency and selectivity. In this review, we provide a broad overview of PCs by explaining their structures, fabrication techniques, and sensing principles. Furthermore, we discuss recent applications of PC-based biosensors incorporated with emerging technologies, including telemedicine, flexible and wearable sensing, smart materials and metamaterials. Finally, we discuss current challenges associated with existing biosensors, and provide an outlook for PC-based biosensors and their promise at the POC.

Indexed as

Biosensing TechniquesPhotonsPoint-of-Care SystemsHumansNanostructures

Identifiers

PMID27841420
PMCPMC5529146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.