Evidence map›Paper›PMID 27841361›Full record

ArticleScientific reports2016

High and Heterogeneous Prevalence of Asymptomatic and Sub-microscopic Malaria Infections on Islands in Lake Victoria, Kenya.

Zulkarnain Md Idris, Chim W Chan, James Kongere, Jesse Gitaka, John Logedi, Ahmeddin Omar, Charles Obonyo, Beatrice Kemunto Machini, Rie Isozumi, Isao Teramoto and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Global patterns of submicroscopicThe Lancet. Microbe · 2021
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  14. Cross-reactivity of rbioRxiv : the preprint server for biology · 2024
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  17. Genetic variation of theFrontiers in parasitology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zulkarnain Md IdrisIsland Malaria Group, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 17177, Sweden.
Chim W ChanIsland Malaria Group, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 17177, Sweden.
James KongereNagasaki University Nairobi Research Station, NUITM-KEMRI Project, Nairobi, 00202, Kenya.
Jesse GitakaDepartment of Clinical Medicine, Mount Kenya University, Thika, 01000, Kenya.
John LogediNational Malaria Control Programme, Ministry of Public Health and Sanitation, Nairobi, 00100, Kenya.
Ahmeddin OmarNational Malaria Control Programme, Ministry of Public Health and Sanitation, Nairobi, 00100, Kenya.
Charles ObonyoKenya Medical Research Institute (KEMRI), Centre for Global Health Research, Kisumu, 40100, Kenya.
Beatrice Kemunto MachiniNational Malaria Control Programme, Ministry of Public Health and Sanitation, Nairobi, 00100, Kenya.
Rie IsozumiDepartment of Parasitology, Graduate School of Medicine, Osaka City University, Osaka, 558-8585, Japan.
Isao TeramotoDepartment of Parasitology, Graduate School of Medicine, Osaka City University, Osaka, 558-8585, Japan.
Masatsugu KimuraDepartment of Parasitology, Graduate School of Medicine, Osaka City University, Osaka, 558-8585, Japan.
Akira KanekoIsland Malaria Group, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 17177, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kenya is intensifying its national efforts in malaria control to achieve malaria elimination. Detailed characterization of malaria infection among populations living in the areas where the disease is endemic in Kenya is a crucial priority, especially for planning and evaluating future malaria elimination strategy. This study aimed to investigate the distribution and extent of malaria infection on islands in Lake Victoria of Kenya to aid in designing new interventions for malaria elimination. Five cross-sectional surveys were conducted between January 2012 and August 2014 on four islands (Mfangano, Takawiri, Kibuogi and Ngodhe) in Lake Victoria and a coastal mainland (Ungoye). Malaria prevalence varied significantly among settings: highest in Ungoye, followed by the large island of Mfangano and lowest in the three remaining small islands. Of the 3867 malaria infections detected by PCR, 91.8% were asymptomatic, 50.3% were sub-microscopic, of which 94% were also asymptomatic. We observed geographical differences and age dependency in both proportion of sub-microscopic infections and asymptomatic parasite carriage. Our findings highlighted the local heterogeneity in malaria prevalence on islands and a coastal area in Lake Victoria, and provided support for the inclusion of mass drug administration as a component of the intervention package to eliminate malaria on islands.

Indexed as

Endemic DiseasesAdolescentAdultChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantInfant, NewbornIslandsKenyaMalariaMalePlasmodiumPrevalence

Identifiers

PMID27841361
PMCPMC5107902

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.