ArticleNature communications2016
Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 51 citations in OpenAlex.
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- Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance.Nature neuroscience · 2025Article
- Unraveling the interplay of circadian rhythm and sleep deprivation on mood: A Real-World Study on first-year physicians.PLOS digital health · 2024Article
- Kv12-encoded K+ channels drive the day-night switch in the repetitive firing rates of SCN neurons.The Journal of general physiology · 2023Article
- ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice.Communications biology · 2023Article
- Plasticity manifolds and degeneracy govern circadian oscillations of neuronal intrinsic properties in the suprachiasmatic nucleus.iScience · 2023Article
- Kv12-Encoded KbioRxiv : the preprint server for biology · 2023Article
- Circadian rhythm of plasminogen activator inhibitor-1 and cardiovascular complications in type 2 diabetes.Frontiers in endocrinology · 2023Review
- WNT/β-catenin Pathway: a Possible Link Between Hypertension and Alzheimer's Disease.Current hypertension reports · 2022Review
- Poly-dipeptides produced fromProceedings of the National Academy of Sciences of the United States of America · 2022Article
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- Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice.Neurobiology of disease · 2021Article
- Salient brain entities labelled in P2rx7-EGFP reporter mouse embryos include the septum, roof plate glial specializations and circumventricular ependymal organs.Brain structure & function · 2021Article
- A Crosstalk between the Biorhythms and Gatekeepers of Longevity: Dual Role of Glycogen Synthase Kinase-3.Biochemistry. Biokhimiia · 2021Review
- The Ketamine Antidepressant Story: New Insights.Molecules (Basel, Switzerland) · 2020Review
- Gene-set Enrichment with Mathematical Biology (GEMB).GigaScience · 2020Article
- Ion Channels Controlling Circadian Rhythms in Suprachiasmatic Nucleus Excitability.Physiological reviews · 2020Review
- Molecular Mechanisms Underlying the Circadian Rhythm of Blood Pressure in Normotensive Subjects.Current hypertension reports · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
How neurons encode intracellular biochemical signalling cascades into electrical signals is not fully understood. Neurons in the central circadian clock in mammals provide a model system to investigate electrical encoding of biochemical timing signals. Here, using experimental and modelling approaches, we show how the activation of glycogen synthase kinase 3 (GSK3) contributes to neuronal excitability through regulation of the persistent sodium current (I
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.