Trial reportScientific reports2016
Disrupted Topological Patterns of Large-Scale Network in Conduct Disorder.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Modular organization of functional brain networks in patients with degenerative cervical myelopathy.Scientific reports · 2024Article
- Brain Anatomy in Boys with Conduct Disorder: Differences Among Aggression Subtypes.Child psychiatry and human development · 2024Article
- Antisocial behavior is associated with reduced frontoparietal network efficiency in youth.Social cognitive and affective neuroscience · 2023Article
- Conduct disorder symptomatology is associated with an altered functional connectome in a large national youth sample.Development and psychopathology · 2022Article
- Towards understanding neurocognitive mechanisms of parenting: Maternal behaviors and structural brain network organization in late childhood.Human brain mapping · 2021Article
- Effects of BDNF Val66Met polymorphisms on brain structures and behaviors in adolescents with conduct disorder.European child & adolescent psychiatry · 2020Article
- Abnormal Gray Matter Structural Covariance Networks in Children With Bilateral Cerebral Palsy.Frontiers in human neuroscience · 2019Article
- Atypical Frontotemporal Connectivity of Cognitive Empathy in Male Adolescents With Conduct Disorder.Frontiers in psychology · 2018Article
- Impaired Efficiency and Resilience of Structural Network in Spinocerebellar Ataxia Type 3.Frontiers in neuroscience · 2018Article
- Alterations of Brain Functional Architecture Associated with Psychopathic Traits in Male Adolescents with Conduct Disorder.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regional abnormalities in brain structure and function, as well as disrupted connectivity, have been found repeatedly in adolescents with conduct disorder (CD). Yet, the large-scale brain topology associated with CD is not well characterized, and little is known about the systematic neural mechanisms of CD. We employed graphic theory to investigate systematically the structural connectivity derived from cortical thickness correlation in a group of patients with CD (N = 43) and healthy controls (HCs, N = 73). Nonparametric permutation tests were applied for between-group comparisons of graphical metrics. Compared with HCs, network measures including global/local efficiency and modularity all pointed to hypo-functioning in CD, despite of preserved small-world organization in both groups. The hubs distribution is only partially overlapped with each other. These results indicate that CD is accompanied by both impaired integration and segregation patterns of brain networks, and the distribution of highly connected neural network 'hubs' is also distinct between groups. Such misconfiguration extends our understanding regarding how structural neural network disruptions may underlie behavioral disturbances in adolescents with CD, and potentially, implicates an aberrant cytoarchitectonic profiles in the brain of CD patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.