ArticleBio-protocol2016
Generation of Mitochondrial-nuclear eXchange Mice via Pronuclear Transfer.
Article in Bio-protocol, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 31 citations in OpenAlex.
- Mitochondrial Genetic Background Shapes Baseline Retinal Function, Age-Related Bioenergetic Remodeling, and Microglial STING Phenotypes.Aging cell · 2026Article
- Mitochondrial tRNA-Derived Fragments as Candidate Metastasis-Modifying RNA.Cancer research communications · 2026Article
- Multi-tissue metabolomics reveal mtDNA- and diet-specific metabolite profiles in a mouse model of cardiometabolic disease.Redox biology · 2025Article
- Preclinical models of mitochondrial dysfunction: mtDNA and nuclear-encoded regulators in diverse pathologies.Frontiers in aging · 2025Review
- Increased Diabetes Complications in a Mouse Model of Oxidative Stress Due to 'Mismatched' Mitochondrial DNA.Antioxidants (Basel, Switzerland) · 2024Article
- Mitochondrial Transfer to Host Cells from Ex Vivo Expanded Donor Hematopoietic Stem Cells.Cells · 2023Article
- Mitochondrial haplotype modulates genome expression and mitochondrial structure/function in cardiomyocytes following volume overload.American journal of physiology. Heart and circulatory physiology · 2023Article
- Roles of mitochondrial genetics in cancer metastasis.Trends in cancer · 2022Review
- Mechanisms of breast cancer metastasis.Clinical & experimental metastasis · 2022Review
- Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat.Physiological research · 2021Review
- Mito-Mendelian interactions alter in vivo glucose metabolism and insulin sensitivity in healthy mice.American journal of physiology. Endocrinology and metabolism · 2021Article
- An evolutionary, or "Mitocentric" perspective on cellular function and disease.Redox biology · 2020Review
- Mitochondrial genetics cooperate with nuclear genetics to selectively alter immune cell development/trafficking.Biochimica et biophysica acta. Molecular basis of disease · 2020Article
- Mitochondrial Haplotype of the Host Stromal Microenvironment Alters Metastasis in a Non-cell Autonomous Manner.Cancer research · 2020Article
- Swapping mitochondria: a key to understanding susceptibility to neonatal chronic lung disease.American journal of physiology. Lung cellular and molecular physiology · 2019Article
- Review
- The second genome: Effects of the mitochondrial genome on cancer progression.Advances in cancer research · 2019Article
- Mitochondrial polymorphisms contribute to aging phenotypes in MNX mouse models.Cancer metastasis reviews · 2018Article
- Roles of the mitochondrial genetics in cancer metastasis: not to be ignored any longer.Cancer metastasis reviews · 2018Review
- Mitochondrial - nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivo.EBioMedicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The mitochondrial paradigm for common disease proposes that mitochondrial DNA (mtDNA) sequence variation can contribute to disease susceptibility and progression. To test this concept, we developed the Mitochondrial-nuclear eXchange (MNX) model, in which isolated embryonic pronuclei from one strain of species are implanted into an enucleated embryo of a different strain of the same species (
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.