Evidence map›Paper›PMID 27840695›Full record

ArticleThe journal of pathology. Clinical research2016

Optimized p53 immunohistochemistry is an accurate predictor of

Martin Köbel, Anna M Piskorz, Sandra Lee, Shuhong Lui, Cecile LePage, Francesco Marass, Nitzan Rosenfeld, Anne-Marie Mes Masson, James D Brenton

Open access · goldAbstract read
In one paragraph

Article in The journal of pathology. Clinical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 198 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
198citing papers in PubMed, 4 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

198 citing papers in PubMed, 4 syntheses or guidelines pooled it, 385 citations in OpenAlex.

  1. Pooled it
  2. Recommendations for diagnosing STIC: a systematic review and meta-analysis.Virchows Archiv : an international journal of pathology · 2022
    Pooled it
  3. Pooled it
  4. Biological tumor markers associated with local control after primary radiotherapy in laryngeal cancer: A systematic review.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2020
    Pooled it
  5. Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Trial
  6. p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022
    Trial
  7. Biomolecules · 2020
    Trial
  8. Article
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  10. Article
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  12. Article
  13. Evaluation of HER2 and Nectin-4 Expression in Primary Vaginal Cancers.International journal of molecular sciences · 2026
    Article
  14. Article
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  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

138 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Martin KöbelDepartment of Pathology and Laboratory Medicine University of Calgary Calgary AB Canada.
Anna M PiskorzCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre Cambridge CB2 0RE UK.
Sandra LeeDepartment of Pathology and Laboratory Medicine University of Calgary Calgary AB Canada.
Shuhong LuiDepartment of Pathology and Laboratory Medicine University of Calgary Calgary AB Canada.
Cecile LePageCentre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM)MontrealQCCanada; Institut du cancer de Montréal, MontrealQCCanada.
Francesco MarassCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre Cambridge CB2 0RE UK.
Nitzan RosenfeldCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre Cambridge CB2 0RE UK.
Anne-Marie Mes MassonCentre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM)MontrealQCCanada; Institut du cancer de Montréal, MontrealQCCanada.
James D BrentonCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre Cambridge CB2 0RE UK.
University of Calgary · CAUniversity of Cambridge · GBCentre Hospitalier de l’Université de Montréal · CACancer Research UK · GB

Funding

Cancer Research UK 15601Cancer Research UK 20240Cancer Research UK 22905Cancer Research UK A15601
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkerendometrioid ovarian carcinomahigh grade serous ovarian carcinomaimmunohistochemistrynext‐generation‐sequencingp53predictionTP53

Identifiers

PMID27840695
PMCPMC5091634
OpenAlexW2417320495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.