Evidence map›Paper›PMID 27840315›Full record

ReviewFree radical biology & medicine2017

Gut microbiota modulate host immune cells in cancer development and growth.

Susan E Erdman, Theofilos Poutahidis

Open access · greenAbstract readReview
In one paragraph

Review in Free radical biology & medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Drug Response Diversity: A Hidden Bacterium?Journal of personalized medicine · 2021
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Synthetic Biology and the Gut Microbiome.Biotechnology journal · 2018
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Susan E ErdmanDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: serdman@mit.edu.
Theofilos PoutahidisDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Pathology, College of Veterinary Medicine, Aristotle University, Thessaloniki, Greece.
Massachusetts Institute of Technology · US

Funding

TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LEVINE, STUART S · 1985 to 2020
$25.6M
GI Tract Dysbiosis and Breast CancerU01CA164337 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ERDMAN, SUSAN E, WANG, TIMOTHY CRAGIN · 2012 to 2016
$2.6M
Role of IL10 and TGFb1 in colon cancerR01CA108854 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ERDMAN, SUSAN E · 2005 to 2014
$2.4M
NCI NIH HHS R01 CA108854NCI NIH HHS U01 CA164337NIEHS NIH HHS P30 ES002109
6 · The paper itself

Abstract

Emerging evidence shows that microbe interactions with the host immune system impact diverse aspects of cancer development and treatment. As a result, exciting new opportunities exist for engineering diets and microbe cocktails to lower cancer risks with fewer adverse clinical effects than traditional strategies. Microbe-based therapies may ultimately be used to reinforce host immune balance and extinguish cancer for generations to come.

Indexed as

AnimalsCarcinogenesisCD4-Positive T-LymphocytesGastrointestinal MicrobiomeHomeostasisHumansImmunity, InnateNeoplasmsProtective FactorsBacteriaHealthHomeostasisHygieneLymphocyteNeutrophilThymus

Identifiers

PMID27840315
PMCPMC5831246
OpenAlexW2556077661

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.