Evidence map›Paper›PMID 27840249›Full record

ArticleBehavioural brain research2017

Mapping the dynamics of cortical neuroplasticity of skilled motor learning using micro X-ray fluorescence and histofluorescence imaging of zinc in the rat.

Mariam Alaverdashvili, Phyllis G Paterson

Open access · greenAbstract read
In one paragraph

Article in Behavioural brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mariam AlaverdashviliNeuroscience Research Cluster, Saskatoon, SK, S7N 5E5, Canada; College of Pharmacy and Nutrition, Saskatoon, SK, S7N 5E5, Canada; College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 5E5, Canada. Electronic address: mariam.alaverdashvili@usask.ca.
Phyllis G PatersonNeuroscience Research Cluster, Saskatoon, SK, S7N 5E5, Canada; College of Pharmacy and Nutrition, Saskatoon, SK, S7N 5E5, Canada.
Innovation Cluster (Canada) · CA

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
CIHR 111124CIHR 111124-1NIGMS NIH HHS P41 GM103393
6 · The paper itself

Abstract

Synchrotron-based X-ray fluorescence imaging (XFI) of zinc (Zn) has been recently implemented to understand the efficiency of various therapeutic interventions targeting post-stroke neuroprotection and neuroplasticity. However, it is uncertain if micro XFI can resolve neuroplasticity-induced changes. Thus, we explored if learning-associated behavioral changes would be accompanied by changes in cortical Zn concentration measured by XFI in healthy adult rats. Proficiency in a skilled reach-to-eat task during early and late stages of motor learning served as a functional measure of neuroplasticity. c-Fos protein and vesicular Zn expression were employed as indirect neuronal measures of brain plasticity. A total Zn map (20×20×30μm

Indexed as

AnimalsCerebral CortexHistological TechniquesLearningMaleMotor SkillsNeuroimagingNeuronal PlasticityOptical ImagingProto-Oncogene Proteins c-fosRatsSynchrotronsZincProto-Oncogene Proteins c-fosZincMicro X-ray fluorescence imagingNeural efficiencyNeural plasticitySkilled motor learningSynchrotronZinc

Identifiers

PMID27840249
PMCPMC5478375
OpenAlexW2554047397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.