Evidence map›Paper›PMID 27838885›Full record

ArticleEndocrine pathology2017

Pathological and Genetic Characterization of Bilateral Adrenomedullary Hyperplasia in a Patient with Germline MAX Mutation.

Pauline Romanet, Carole Guerin, Pascal Pedini, Wassim Essamet, Frédéric Castinetti, Fréderic Sebag, Philippe Roche, Alberto Cascon, Arthur S Tischler, Karel Pacak and 2 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in Endocrine pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Adrenal Medullary Hyperplasia: A Systematic Review and Meta-analysis.The Journal of clinical endocrinology and metabolism · 2023
    Pooled it
  2. Review
  3. The evolving roles of pathologists in paragangliomas and pheochromocytomas.Virchows Archiv : an international journal of pathology · 2026
    Review
  4. Article
  5. Review
  6. Genotype and clinical phenotype characteristics ofFrontiers in endocrinology · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. A Novel, Likely PathogenicJournal of the Endocrine Society · 2021
    Article
  11. Somatotroph Tumors and the Epigenetic Status of theInternational journal of molecular sciences · 2021
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. 18F-FDOPA PET/CT Imaging of MAX-Related Pheochromocytoma.The Journal of clinical endocrinology and metabolism · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Pauline RomanetLaboratory of Molecular Biology, Aix Marseille University CNRS, CRN2M, Marseille, France & APHM Conception, 13385, Marseille, France.
Carole GuerinDepartment of Endocrine Surgery, Aix-Marseille University Marseille, France & APHM Conception, 13284, Marseille, France.
Pascal PediniLaboratory of Molecular Biology, Aix Marseille University CNRS, CRN2M, Marseille, France & APHM Conception, 13385, Marseille, France.
Wassim EssametAPHM Timone Department of Neuropathology, Marseille, France.
Frédéric CastinettiDepartment of Endocrinology, Aix Marseille University, CNRS, CRN2M, Marseille, France & APHM Conception, Marseille, France.
Fréderic SebagDepartment of Endocrine Surgery, Aix-Marseille University Marseille, France & APHM Conception, 13284, Marseille, France.
Philippe RocheIntegrative Structural & Chemical Biology (iSCB) & INT-3D Molecular Modeling Platform, Cancer Research Centre of Marseille, CNRS UMR7258; INSERM U1068; Institut Paoli Calmettes; Aix-Marseille University, UM105, Marseille, France.
Alberto CasconHereditary Endocrine Cancer Group, Spanish National Cancer Research Centre and Centro de Investigación Biomédica en Red de Enfermedades Raras, Madrid, Spain.
Arthur S TischlerDepartment of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USA.
Karel PacakSection on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institutes of Health, Bethesda, MD, 20892, USA.
Anne BarlierLaboratory of Molecular Biology, Aix Marseille University CNRS, CRN2M, Marseille, France & APHM Conception, 13385, Marseille, France.
David TaïebDepartment of Nuclear Medicine, La Timone University Hospital & CERIMED & Inserm UMR1068 Marseille Cancerology Research Center, Institut Paoli-Calmettes, Aix Marseille University, 264 Rue Saint-Pierre, 13385, Marseille, France. david.taieb@ap-hm.fr.
Hôpital de la Conception · FRAix-Marseille Université · FRCentre de Recherche en Neurobiologie - Neurophysiologie de Marseille · FRCentre for Biomedical Network Research on Rare Diseases · ESEunice Kennedy Shriver National Institute of Child Health and Human Development · USHôpital de la Timone · FRInserm · FRInstitut Paoli-Calmettes · FRTufts Medical Center · US

Funding

Diagnosis, Pathophysiology And Molecular Biology of Pheochromocytoma and ParagangliomaZIAHD008735 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PACAK, KAREL · 2009 to 2024
$28.4M
Intramural NIH HHS ZIA HD008735
6 · The paper itself

Abstract

In recent years, familial pheochromocytoma (PHEO) with germline mutations in the MAX (MYC associated factor X) gene has been reported in a few cases. Here, we investigated a 25-year-old patient with multiple PHEOs associated with a non-sense germline MAX mutation. Preoperative

Indexed as

Adrenal Gland NeoplasmsAdrenal GlandsAdultBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCodon, NonsenseGenetic Predisposition to DiseaseGerm-Line MutationHumansHyperplasiaMalePheochromocytomaBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCodon, NonsenseMAX protein, humanAdrenal medullary hyperplasiaMAXMYC-associated factor XPheochromocytoma

Identifiers

PMID27838885
PMCPMC6287616
OpenAlexW2550016662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.