ArticleInternational journal of colorectal disease2017
Laparoscopic surgery should be considered in T4 colon cancer.
Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Risk of peritoneal metastasis following minimally invasive colectomy for locally advanced colon cancer: a systematic review and meta-analysis.The oncologist · 2025Pooled it
- Laparoscopic surgery for T4 colon cancer: a systematic review and meta-analysis.Surgical endoscopy · 2017Pooled it
- Techniques, perioperative outcomes, prognosis, and survival associated with laparoscopic surgery for T3-T4a colon cancer.World journal of gastrointestinal oncology · 2025Article
- Article
- Should be a locally advanced colon cancer still considered a contraindication to laparoscopic resection?Surgical endoscopy · 2022Article
- Laparoscopic vs. open colectomy for T4 colon cancer: A meta-analysis and trial sequential analysis of prospective observational studies.Frontiers in surgery · 2022Review
- Oncological outcomes following laparoscopic surgery for pathological T4 colon cancer: a propensity score-matched analysis.Surgery today · 2021Article
- Favorable short-term oncologic outcomes following laparoscopic surgery for small T4 colon cancer: a multicenter comparative study.World journal of surgical oncology · 2020Article
- The Short- and Long-Term Feasibility of Laparoscopic Surgery in Colon Cancer Patients with Bulky Tumors.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
- Outcomes of laparoscopic surgery for pathological T4 colon cancer.International journal of colorectal disease · 2019Article
- Laparoscopic surgery facilitates administration of adjuvant chemotherapy in locally advanced colon cancer: propensity score analyses.Cancer management and research · 2019Article
- Impact of postoperative complications on long-term survival following surgery for T4 colorectal cancer.BMC surgery · 2018Article
- Long-term oncologic outcomes after laparoscopic vs. open colon cancer resection: a high-quality population-based analysis in a Southern German district.Surgical endoscopy · 2018Observational
- Laparoscopic surgery for locally advanced T4 colon cancer: the long-term outcomes and prognostic factors.Surgery today · 2018Article
- Laparoscopy-assisted colectomy as an Oncologically safe alternative for patients with stage T4 Colon Cancer: a propensity-matched cohort study.BMC cancer · 2018Article
- Short- and long-term outcomes following laparoscopicWorld journal of gastroenterology · 2018Article
- Editorial comment on: Laparoscopic resection for colorectal diseases: short-term outcomes of a single center.Turkish journal of surgery · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLaparoscopy in T4 colon cancers is not widely advocated due to concerns regarding safety and oncologic efficacy. We conducted this study to compare the short- and long-term oncological outcomes between laparoscopic and open approaches in T4 colon cancers.
methodsA retrospective analysis of all patients who underwent surgery for T4 colon cancer from 2008 to 2014 was performed. Margin positive rate, lymph node yield, local or distant recurrence and overall survival were analysed.
resultsA total of 59 patients received open surgery, whilst 93 underwent laparoscopic surgery, with a conversion rate of 8.6%. There was no difference in the various measured outcomes between the laparoscopic and open groups. The relative risks of positive margins and inadequate lymph node yield for staging were 0.95 (0.74-1.23, p = 0.692) and 1.01 (0.97-1.05, p = 0.710), respectively, for the laparoscopic group when compared to the open approach. Regarding long-term outcomes, the relative risk of local recurrence in the laparoscopic group was 0.99 (0.96-1.02, p = 0.477), whilst there were also no increased risks of developing distal recurrences at the liver (RR 1.19, 0.51-2.82, p = 0.684), lungs (RR 1.20, 0.50-2.87, p = 0.678) and peritoneum (RR 1.22, 0.51-2.95, p = 0.653) in the laparoscopic group. There was also no difference in the overall survival (RR 0.70, 0.42-1.16, p = 0.168). Patients were followed up for a median of 73.3 months (range 34.8-144.7).
conclusionLaparoscopic surgery does not compromise oncological outcomes in T4 colon cancers compared to the open approach. Because of its proven associated benefits, laparoscopy should be considered in selected T4 colon cancers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.