Evidence map›Paper›PMID 27838794›Full record

ArticleJournal of bone and mineral metabolism2017

Physical activity may be a potent regulator of bone turnover biomarkers in healthy girls during preadolescence.

Antonis Kambas, Diamanda Leontsini, Alexandra Avloniti, Athanasios Chatzinikolaou, Theodoros Stampoulis, Konstantinos Makris, Dimitrios Draganidis, Athanasios Z Jamurtas, Symeon Tournis, Ioannis G Fatouros

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Article in Journal of bone and mineral metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Exercise Early and Often: Effects of Physical Activity and Exercise on Women's Bone Health.International journal of environmental research and public health · 2018
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antonis KambasDepartment of Physical Education and Sport Science, Democritus University of Thrace, Komotini, Greece.
Diamanda LeontsiniDepartment of Physical Education and Sport Science, Democritus University of Thrace, Komotini, Greece.
Alexandra AvlonitiDepartment of Physical Education and Sport Science, Democritus University of Thrace, Komotini, Greece.
Athanasios ChatzinikolaouDepartment of Physical Education and Sport Science, Democritus University of Thrace, Komotini, Greece.
Theodoros StampoulisDepartment of Physical Education and Sport Science, Democritus University of Thrace, Komotini, Greece.
Konstantinos MakrisClinical Biochemistry Department, KAT Hospital, Kifissia, Athens, Greece.
Dimitrios DraganidisSchool of Physical Education and Sports Sciences, University of Thessaly, Karies, Trikala, 42100, Greece.
Athanasios Z JamurtasSchool of Physical Education and Sports Sciences, University of Thessaly, Karies, Trikala, 42100, Greece.
Symeon TournisLaboratory of Research of Musculoskeletal System "Th. Garofalidis", University of Athens, KAT Hospital, Athens, Greece.
Ioannis G FatourosSchool of Physical Education and Sports Sciences, University of Thessaly, Karies, Trikala, 42100, Greece. ifatouros@pe.uth.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of different levels of habitual physical activity (PA) assessed by pedometry on bone turnover markers of preadolescent girls according to a cross-sectional experimental design. Sixty prepubertal girls of similar chronological age, bone age, maturity level, and nutritional status were assigned to a low PA (LPA; n = 25), a moderate PA (MPA; n = 17), or a high PA (HPA; n = 18) group. Dual-energy X-ray absorptiometry was used to measure areal bone mineral density (BMD) and bone mineral content (BMC) of the lumbar spine (L2-L4) and dominant hip (femoral neck and trochanter). Blood was collected for the measurement of alkaline phosphatase (ALP), bone-specific ALP (BSAP), procollagen type I N-terminal propeptide (PINP), C-terminal telopeptide of collagen I (CTX), parathyroid hormone (PTH), osteocalcin, thyroid-stimulating hormone, estradiol, testosterone, luteinizing hormone, and follicle-stimulating hormone concentrations. ANOVA revealed that the HPA group (18,695 ± 1244 steps per day) had a lower daily energy intake and body mass than the MPA group (10,774 ± 521 steps per day) and the LPA group (7633 ± 1099 steps per day). The HPA group had higher (P < 0.05) lumbar and hip BMD and hip BMC than the LPA group and higher (P < 0.05) lumbar BMD than the MPA group. The MPA group had higher (P < 0.05) hip BMC than the LPA group. The HPA group had greater (P < 0.05) values of BSAP, PINP, and ALP and lower (P < 0.05) values of PTH and CTX than the LPA group but not the MPA group. A partial correlation analysis (adjusted for body mass index) revealed a positive correlation of steps per day with BMD and BSAP concentration and a negative correlation with PTH and CTX concentration. In conclusion, PA increases BMD and BMC of premenarcheal girls by favoring bone formation over bone resorption.

Indexed as

ExerciseAbsorptiometry, PhotonAdolescentBiomarkersBone DensityBone RemodelingChildCross-Sectional StudiesFemaleHumansBiomarkersBone markersBone remodelingChildrenPhysical activityPreadolescence

Identifiers

PMID27838794

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.