ArticleEuropean journal of nuclear medicine and molecular imaging2017
The clinical utility of FDG PET/CT among solid organ transplant recipients suspected of malignancy or infection.
Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Article
- Febrile Immunocompromised Renal Transplant Recipient with Allograft Dysfunction: Detection of an Undiagnosed Prostate Abscess by [World journal of nuclear medicine · 2024Article
- Clinical Utility ofJournal of imaging · 2023Article
- Imaging of pediatric hematopoietic stem cell transplant recipients: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper.Pediatric blood & cancer · 2023Article
- SNMMI Procedure Standard/EANM Practice Guideline on PediatricJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
- Assessment of Suspected Malignancy or Infection in Immunocompromised Patients After Solid Organ Transplantation by [Nuclear medicine and molecular imaging · 2020Article
- Diagnostic Performance ofDiagnostics (Basel, Switzerland) · 2020Review
- Application of animal and human PET in cardiac research.American journal of cardiovascular disease · 2018Review
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11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSolid organ transplant (SOT) recipients are at high risk of developing infections and malignancies.
methodsRecipients with a post-transplant FDG PET/CT performed as part of diagnostic work-up were included. Detailed chart reviews were done to extract relevant clinical information and determine the final diagnosis related to the FDG PET/CT. Based on á priori defined criteria and the final diagnosis, results from each scan were classified as true or false, and diagnostic values determined.
resultsAmong the 1,814 recipients in the cohort, 145 had an FDG PET/CT performed; 122 under the indication of diagnostically unresolved symptoms with a suspicion of malignancy or infection. The remaining (N = 23) had an FDG PET/CT to follow-up on a known disease or to stage a known malignancy. The 122 recipients underwent a total of 133 FDG PET/CT scans performed for a suspected malignancy (66 %) or an infection (34 %). Sensitivity, specificity, and positive and negative predictive values of the FDG PET/CT in diagnosing these conditions were 97, 84, 87, and 96 %, respectively.
conclusionFDG PET/CT is an accurate diagnostic tool for the work-up of diagnostic unresolved SOT recipients suspected of malignancy or infection. The high sensitivity and NPV underlines the potential usefulness of PET/CT for excluding malignancy or focal infections in this often complex clinical situation.
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