Evidence map›Paper›PMID 27838441›Full record

ReviewNeurobiology of learning and memory2017

Reconsolidation and psychopathology: Moving towards reconsolidation-based treatments.

Amber B Dunbar, Jane R Taylor

Abstract readReview
In one paragraph

Review in Neurobiology of learning and memory, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 67 citations in OpenAlex.

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  13. mTOR inhibition impairs extinction memory reconsolidation.Learning & memory (Cold Spring Harbor, N.Y.) · 2021
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amber B DunbarDepartment of Psychiatry, Division of Molecular Psychiatry, New Haven, CT 06520, USA; Department of Psychology, Yale University, New Haven, CT 06520, USA.
Jane R TaylorDepartment of Psychiatry, Division of Molecular Psychiatry, New Haven, CT 06520, USA; Department of Psychology, Yale University, New Haven, CT 06520, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA. Electronic address: jane.taylor@yale.edu.
Yale University · US

Funding

Individual differences & cocaine effects on impulsive choice in rats: D3/5HT1B R01DA043443 · NIDA · YALE UNIVERSITY · PI Jane R Taylor · 2016 to 2026
$4.6M
Incentive Motivation in Addiction: PKA MechanismsR01DA015222 · NIDA · YALE UNIVERSITY · PI TAYLOR, JANE R · 2003 to 2013
$2.7M
NIDA NIH HHS R01 DA015222NIDA NIH HHS R01 DA043443
6 · The paper itself

Abstract

Interfering with memory reconsolidation has valuable potential to be used as a treatment for maladaptive memories and psychiatric disorders. Numerous studies suggest that reconsolidation-based therapies may benefit psychiatric populations, but much remains unanswered. After reviewing the literature in clinical and healthy human populations, we discuss some of the major limitations to reconsolidation studies and clinical application. Finally, we provide recommendations for developing improved reconsolidation-based treatments, namely exploiting known boundary conditions and focusing on a novel unconditioned stimulus-retrieval paradigm.

Indexed as

HumansMemory ConsolidationMental DisordersPsychotherapyAddictionGarcinolPsychopathologyPTSDReconsolidationSchizophrenia

Identifiers

PMID27838441
PMCPMC5423865
OpenAlexW2551326840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.