Evidence map›Paper›PMID 27838383›Full record

ArticleOsteoarthritis and cartilage2017

Cross-sectional and longitudinal study of the impact of posterior meniscus horn lesions on adjacent cartilage composition, patient-reported outcomes and gait biomechanics in subjects without radiographic osteoarthritis.

C Russell, V Pedoia, R B Souza, S Majumdar

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoarthritis and cartilage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Combined Injury to the ACL and Lateral Meniscus Alters the Geometry of Articular Cartilage and Meniscus Soon After Initial Trauma.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  3. Osteoarthritis year in review 2018: mechanics.Osteoarthritis and cartilage · 2019
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

C RussellMusculoskeletal Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA. Electronic address: Colin.Russell@tufts.edu.
V PedoiaMusculoskeletal Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA. Electronic address: Valentina.Pedoia@ucsf.edu.
R B SouzaMusculoskeletal Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA; Department of Physical Therapy, University of California, San Francisco, San Francisco, CA, USA. Electronic address: Richard.Souza@ucsf.edu.
S MajumdarMusculoskeletal Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA. Electronic address: Sharmila.Majumdar@ucsf.edu.
University of California, San Francisco · US

Funding

MRI TO STUDY CARTILAGE/BONE INTERACTIONSR01AR046905 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA · 1999 to 2015
$6.3M
Translation of Quantitative Imaging in OsteoarthritisP50AR060752 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOUZA, RICHARD BRIAN · 2011 to 2015
$6.2M
Contact mechanics, neuromuscular control, and cartilage composition in knee OAR01AR062370 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOUZA, RICHARD BRIAN · 2011 to 2014
$1.1M
NIAMS NIH HHS P50 AR060752NIAMS NIH HHS R01 AR046905NIAMS NIH HHS R01 AR062370
6 · The paper itself

Abstract

objectiveThe aim of this study was to assess cross-sectional and longitudinal effects of meniscal lesions on adjacent cartilage T

designThirty patients with no cartilage morphological defects reported by Whole Organ MRI Score (WORMS) magnetic resonance imaging (MRI) grading and no radiographic osteoarthritis (OA) (Kellgren--Lawrence (KL) ≤ 1) were selected, 15 with posterior meniscus horn lesions and 15 matched controls without meniscal lesions. All were imaged on a 3T MR scanner for three consecutive years, except those who dropped from the study. Sagittal and frontal plane kinematic gait data were acquired at baseline. The Knee Injury and Osteoarthritis Outcome Score (KOOS) survey was taken each time. All images were automatically segmented and registered to an atlas for voxel-by-voxel cross-sectional and longitudinal analyses.

resultsRelaxation time comparisons between groups showed elevated T

conclusionsIndividuals with healthy cartilage and posterior meniscal horn lesions have increased relaxation times when compared to matched controls, increased relaxation time changes over 2 years, and consistently report a lower KOOS QOL, yet show no difference in gait biomechanics.

Indexed as

Imaging, Three-DimensionalAdultAgedBiomechanical PhenomenaCartilage, ArticularCartilage DiseasesCross-Sectional StudiesDisease ProgressionFemaleGaitHumansKnee InjuriesLongitudinal StudiesMagnetic Resonance ImagingMaleMenisci, TibialGait analysisKOOSMeniscus lesionT(1ρ)T(2)Voxel-based relaxometry

Identifiers

PMID27838383
PMCPMC7263373
OpenAlexW2555553162

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.