Evidence map›Paper›PMID 27838367›Full record

ArticleJournal of structural biology2017

Real-time detection and single-pass minimization of TEM objective lens astigmatism.

Rui Yan, Kunpeng Li, Wen Jiang

Abstract read
In one paragraph

Article in Journal of structural biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Flaviviruses have imperfect icosahedral symmetry.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rui YanMarkey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
Kunpeng LiMarkey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
Wen JiangMarkey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA. Electronic address: jiang12@purdue.edu.
Purdue University West Lafayette · US

Funding

HBGA receptors in host cell entry and infection of norovirusR01AI111095 · NIAID · PURDUE UNIVERSITY · PI JIANG, WEN, JIANG, XI · 2015 to 2019
$2.5M
NIAID NIH HHS R01 AI111095
6 · The paper itself

Abstract

Minimization of the astigmatism of the objective lens is a critical daily instrument alignment task essential for high resolution TEM imaging. Fast and sensitive detection of astigmatism is needed to provide real-time feedback and adjust the stigmators to efficiently reduce astigmatism. Currently the method used by many microscopists is to visually examine the roundness of a diffractogram (Thon rings) and iteratively adjust the stigmators to make the Thon rings circular. This subjective method is limited by poor sensitivity and potentially biased by the astigmatism of human eyes. In this study, an s

Indexed as

AlgorithmsCryoelectron MicroscopyHumansMicroscopy, Electron, TransmissionModels, TheoreticalSignal-To-Noise RatioAstigmatism correctioncryo-EMObjective lens stigmators“Radar”-style displayReal-time feedbackSingle-pass tuning strategy

Identifiers

PMID27838367
PMCPMC5360486
OpenAlexW2552577460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.