ArticleBiological psychiatry2017
Behavioral and Neural Sustained Attention Deficits in Bipolar Disorder and Familial Risk of Bipolar Disorder.
Article in Biological psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alterations in Task-Related Brain Activation in Children, Adolescents and Young Adults at Familial High-Risk for Schizophrenia or Bipolar Disorder - A Systematic Review.Frontiers in psychiatry · 2020Pooled it
- Evidence for pro-cognitive benefits of cannabinoids in people with bipolar disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Trial
- Executive function performance in high and low medication adherent patients with euthymic bipolar i disorder: a comparative study.BMC psychiatry · 2025Article
- Executive Control and Associated Brain Activity in Children With Familial High-Risk of Schizophrenia or Bipolar Disorder: A Danish Register-based Study.Schizophrenia bulletin · 2024Article
- Causal oscillations in the visual thalamo-cortical network in sustained attention in ferrets.Current biology : CB · 2024Article
- Deficits in sustained attention in adolescents with bipolar disorder during their first manic episode.Journal of affective disorders · 2023Article
- BOLD Response is more than just magnitude: Improving detection sensitivity through capturing hemodynamic profiles.NeuroImage · 2023Article
- Annual Research Review: The contributions of the RDoC research framework on understanding the neurodevelopmental origins, progression and treatment of mental illnesses.Journal of child psychology and psychiatry, and allied disciplines · 2022Review
- Linking RDoC and HiTOP: A new interface for advancing psychiatric nosology and neuroscience.Clinical psychology review · 2021Review
- Article
- Disturbances of Dynamic Function in Patients With Bipolar Disorder I and Its Relationship With Executive-Function Deficit.Frontiers in psychiatry · 2020Article
- Early-childhood social reticence predicts SCR-BOLD coupling during fear extinction recall in preadolescent youth.Developmental cognitive neuroscience · 2019Article
- Article
- Attentional fluctuations in preschoolers: Direct and indirect relations with task accuracy, academic readiness, and school performance.Journal of experimental child psychology · 2018Article
- Timely Research in Bipolar Disorder and Attention-Deficit/Hyperactivity Disorder.Biological psychiatry · 2017Article
- Behavioral and Neural Sustained Attention Deficits in Disruptive Mood Dysregulation Disorder and Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2017Observational
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9 authors.
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Abstract
backgroundFew neuroimaging studies compare individuals affected with bipolar disorder (BP), at high familial risk of BP, and at low risk to identify endophenotypes for BP. None have examined variability in attention, despite promising behavioral work in this area. We used functional magnetic resonance imaging (fMRI) methods uniquely powered to compare the neural correlates of attention variability in these three groups.
methodsThe present study examined 8- to 25-year-old individuals (n = 106) who completed an fMRI attention task: 24 with BP, 29 at risk based on a first-degree relative with BP, and 53 healthy, low-risk individuals. Group differences in intrasubject variability in reaction time were examined, and a sophisticated fMRI analytic approach was used to quantify precisely trialwise associations between reaction time and brain activity. The latter has not been examined previously in BP or risk of BP.
resultsRelative to healthy individuals, those with BP or at risk for BP exhibited increased reaction time variability (F
conclusionsBlunting in key frontal, cingulate, and striatal areas was evident in unaffected, at-risk individuals and in euthymic BP patients. Elucidating such novel neural endophenotypes can facilitate new approaches to BP prediction, diagnosis, and prevention.
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