ArticleJournal of colloid and interface science2017
Probing mucin interaction behavior of magnetic nanoparticles.
Article in Journal of colloid and interface science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- DoE-Optimized Chitosan-Coated pH-Sensitive Liposomes for Targeted Nose-to-Brain Delivery of Temozolomide.AAPS PharmSciTech · 2026Article
- Development of hesperidin loaded lipid-chitosan nanoparticles: physicochemical characterization, molecular docking and ex vivo study.Scientific reports · 2026Article
- Spatial Pharmacokinetic and Pharmacodynamic Modeling in Airway Mucus.Clinical pharmacokinetics · 2025Article
- Nanoencapsulation of vitamin BJournal of food science · 2025Article
- In Vitro Mucoadhesive Features of Gliadin Nanoparticles Containing Thiamine Hydrochloride.Pharmaceutics · 2024Article
- RETRACTED: Design and Evaluation of S-Protected Thiolated-Based Itopride Hydrochloride Polymeric Nanocrystals for Functional Dyspepsia: QbD-Driven Optimization, In Situ, In Vitro, and In Vivo Investigation.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Symmetry breaking propulsion of magnetic microspheres in nonlinearly viscoelastic fluids.Nature communications · 2021Article
- Self-Assembly of Amphiphilic Compounds as a Versatile Tool for Construction of Nanoscale Drug Carriers.International journal of molecular sciences · 2020Review
- Characterisation of the Interaction among Oil-In-Water Nanocapsules and Mucin.Biomimetics (Basel, Switzerland) · 2020Article
- Tannic acid inhibits lipid metabolism and induce ROS in prostate cancer cells.Scientific reports · 2020Article
- Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence.ACS applied materials & interfaces · 2019Article
- Prospects for the Use of New Technologies to Combat Multidrug-Resistant Bacteria.Frontiers in pharmacology · 2019Article
- Interactions of Transition Metal Dichalcogenide Nanosheets With Mucin: Quartz Crystal Microbalance With Dissipation, Surface Plasmon Resonance, and Spectroscopic Probing.Frontiers in chemistry · 2019Article
- A journey from the endothelium to the tumor tissue: distinct behavior between PEO-PCL micelles and polymersomes nanocarriers.Drug delivery · 2018Article
- Article
- Development of polyvinylpyrrolidone/paclitaxel self-assemblies for breast cancer.Acta pharmaceutica Sinica. B · 2018Article
- Magnetic nanoformulations for prostate cancer.Drug discovery today · 2017Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
In this study, we developed iron oxide based magnetic nanoparticles (MNPs) by precipitation of iron salts in the presence of ammonia and created four different formulations: without functionality (plain MNPs, no coating), with β-cyclodextrin (MNPs+β-CD) or pluronic 127 polymer (MNPs+F-127), and both β-cyclodextrin and pluronic 127 polymer (MNPs+β-CD-F-127) functionality for its efficient use in mucosal delivery. We studied the interaction and/or binding behavior of these MNPs formulations with porcine stomach mucin using steady-state fluorescence spectroscopy, and then quantified the bound mucin from absorption studies. Toxicity of these MNPs against cervical cancer cells and red blood cells was evaluated. Ex-vivo studies were performed using freshly collected gastrointestinal, ovarian, pancreas and colon organ tissues of pig to evaluate binding and uptake phenomenon of MNPs. Transport studies of these MNPs in mucin was evaluated using Boyden's chamber assay. All these studies together suggest that the MNPs+β-CD-F-127 formulation was strongly interacted with mucin and interestingly transported through mucin compared to other MNPs formulations. Hence, MNPs+β-CD-F-127 formulation could be a good candidate for the mucoadhesive biopharmaceuticals and drug delivery system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.