ArticleAging clinical and experimental research2017
Pancreatic stump closure after pancreatoduodenectomy in elderly patients: a retrospective clinical study.
Article in Aging clinical and experimental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- The Prognostic Role of Glycemia in Patients With Pancreatic Carcinoma: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2022Pooled it
- Permanent Pancreatic Duct Occlusion With Neoprene-based Glue Injection After Pancreatoduodenectomy at High Risk of Pancreatic Fistula: A Prospective Clinical Study.Annals of surgery · 2019Trial
- The role of the aging process and related factorGenes & diseases · 2025Article
- Optimal surgical management of unifocal vs. multifocal NF-PNETs: a respective cohort study.World journal of surgical oncology · 2024Article
- Understanding autoimmune pancreatitis: Clinical features, management challenges, and association with malignancies.World journal of gastroenterology · 2024Article
- Long-term survivor of giant pancreatic solid pseudopapillary neoplasm with splenic infiltration and lymph node metastasis.BMJ case reports · 2023Article
- Is Surgery in Autoimmune Pancreatitis Always a Failure?Medicina (Kaunas, Lithuania) · 2023Review
- Selective use of pancreatic duct occlusion during pancreaticoduodenectomy in patients with a small-size duct and atrophic parenchyma in the distal pancreas: A retrospective study.Frontiers in surgery · 2022Article
- Clinical Phase I/II Study: Local Disease Control and Survival in Locally Advanced Pancreatic Cancer Treated with Electrochemotherapy.Journal of clinical medicine · 2021Article
- Short-term outcomes after minimally invasive versus open pancreaticoduodenectomy in elderly patients: a propensity score-matched analysis.BMC surgery · 2021Article
- Mucin-filled CBD, difficult to manage cholangitis.BMJ case reports · 2021Article
- Article
- Clinicopathological characteristics and risk factors for recurrence of well-differentiated pancreatic neuroendocrine tumors after radical surgery: a case-control study.World journal of surgical oncology · 2019Article
- Comparison of Different Techniques of Pancreatic Stump Management in Robot-Assisted Pancreaticoduodenectomy.Gastrointestinal tumors · 2019Article
- Rare case of adult pancreatic haemangioma and literature review.BMJ case reports · 2018Article
- Postoperative pancreatic fistula: a review of traditional and emerging concepts.Clinical and experimental gastroenterology · 2018Review
- Genome-scale analysis to identify prognostic markers in patients with early-stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy.OncoTargets and therapy · 2017Article
- Robot-Assisted Simultaneous Distal Pancreatectomy and Sigmoidectomy for Synchronous Pancreatic and Colon Tumors: A Case Report.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPancreatic fistula (PF) after pancreatoduodenectomy (PD) represents the major source of morbidity. Derivative procedures are preferred by pancreatic surgeons, but the optimal management of remnant pancreatic stump remains controversial.
aimsThe purpose of this retrospective study is to evaluate the efficacy and safety of pancreatic stump closure in selected elderly patients (>65 years).
methodsClinical data of 44 PD undergone mechanical closure of the pancreatic stump performed between 2001 and 2014 in two department of general and oncologic surgery were retrospectively collected. Considering the age, patients were divided into two groups: 21 patients of less than 65 years (Group A) and 23 patients of more than 65 years (Group B).
resultsA soft pancreatic parenchyma with a not-dilated duct (diameter <3 mm) was reported in all the 44 patients. A grade-A PF, which did not required further treatments, developed in 20 cases (45.4%; 13 in group A and 7 in group B; p < 0.05), grade-B in 5 patients (11.4%; 3 in group A and 2 in group B; statistically not significant) and a grade-C PF was observed only in one patient (2.2%; 1 in group A and 0 in group B). DISCUSSION: In selected "high risk" elderly patients (>65 years) with soft pancreatic texture, the closure of the pancreatic stump can be a useful tool in the surgical armamentarium with the aim to reduce the incidence of age-related complications.
conclusionsProspective randomized controlled trial to better evaluate PF risk factors is needed.
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