Evidence map›Paper›PMID 27837410›Full record

ArticleImmunologic research2017

Effect of CD40/CD40L signaling on IL-10-producing regulatory B cells in Chinese children with Henoch-Schönlein purpura nephritis.

Baohui Yang, Xiongjun Tan, Xiao Xiong, Daoqi Wu, Gaofu Zhang, Mo Wang, Shifang Dong, Wei Liu, Haiping Yang, Qiu Li

Abstract read
PubMed Publisher
In one paragraph

Article in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Baohui YangMinistry of Education, Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Xiongjun TanMinistry of Education, Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Xiao XiongMinistry of Education, Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Daoqi WuDepartment of Nephroimmunology, Children's Hospital, Chongqing Medical University, Chongqing, China.
Gaofu ZhangDepartment of Nephroimmunology, Children's Hospital, Chongqing Medical University, Chongqing, China.
Mo WangDepartment of Nephroimmunology, Children's Hospital, Chongqing Medical University, Chongqing, China.
Shifang DongMinistry of Education, Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Wei LiuMinistry of Education, Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Haiping YangDepartment of Nephroimmunology, Children's Hospital, Chongqing Medical University, Chongqing, China. oyhp0708@163.com.
Qiu LiDepartment of Nephroimmunology, Children's Hospital, Chongqing Medical University, Chongqing, China. liqiu809@126.com.
Children's Hospital of Chongqing Medical University · CNChongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to examine the role and mechanism of interleukin-10 (IL-10)-producing regulatory B cells (B10 cells) in the pathogenesis of Henoch-Schönlein purpura nephritis (HSPN). We examined the percentage of B10 cells, CD19

Indexed as

AdolescentAntibodies, BlockingB-Lymphocytes, RegulatoryCD40 AntigensCD40 LigandCells, CulturedChildChild, PreschoolChinaHumansIgA VasculitisImmunophenotypingInterleukin-10Lymphocyte CountNephritisSignal TransductionAntibodies, BlockingCD40 AntigensCD40 LigandInterleukin-10CD19 + CD24hiCD27+ B cellsCD19+CD24hiCD38hi B cellsCD40/CD40LHenoch-Schönlein purpura nephritisInterleukin-10-producing regulatory B cellsTh17/Treg

Identifiers

PMID27837410
OpenAlexW2553351694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.