ArticleOphthalmology and therapy2016
Need for Animal Models of Meibomian Gland Dysfunction.
Article in Ophthalmology and therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Recent advances in age-related meibomian gland dysfunction (ARMGD).The ocular surface · 2023Review
- A review of rabbit models of meibomian gland dysfunction and scope for translational research.Indian journal of ophthalmology · 2023Review
- A New Organotypic 3D Slice Culture ofInternational journal of molecular sciences · 2022Article
- The effects of systemic aromatase inhibitors on meibomian glands and corneal structure.Eye (London, England) · 2022Observational
- Experimental Models, Induction Protocols, and Measured Parameters in Dry Eye Disease: Focusing on Practical Implications for Experimental Research.International journal of molecular sciences · 2021Review
- Epithelial stem cell homeostasis in Meibomian gland development, dysfunction, and dry eye disease.JCI insight · 2021Article
- A novel transillumination meibography device for in vivo imaging of mouse meibomian glands.The ocular surface · 2021Article
- Neutrophils cause obstruction of eyelid sebaceous glands in inflammatory eye disease in mice.Science translational medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evaporative dry eye has gained increasing interest in recent years in academia, pharmaceutical, and medical device industries. The main cause of this type of dry eye is attributed to meibomian gland dysfunction (MGD). MGD is a diffuse abnormality of the meibomian glands characterised by terminal duct obstruction and eventually leading to signs and symptoms of dry eye. There have been only a few reported animal models of MGD, but recent advances are likely to lead to new models and better ways to assess the pathology in these animals. Recent models reported include one based on cautery of the meibomian glands in mice and another based on aggravated allergy in mice. These developments will enable better pre-clinical assessment of novel therapies in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.