Evidence map›Paper›PMID 27837379›Full record

ArticleBreast cancer research and treatment2017

Pre-diagnostic breastfeeding, adiposity, and mortality among parous Hispanic and non-Hispanic white women with invasive breast cancer: the Breast Cancer Health Disparities Study.

Avonne E Connor, Kala Visvanathan, Kathy B Baumgartner, Richard N Baumgartner, Stephanie D Boone, Lisa M Hines, Roger K Wolff, Esther M John, Martha L Slattery

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Breast cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Avonne E ConnorDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Office E-6137, Baltimore, MD, 21205, USA. aconnor8@jhu.edu.
Kala VisvanathanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Office E-6137, Baltimore, MD, 21205, USA.
Kathy B BaumgartnerDepartment of Epidemiology and Population Health; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Richard N BaumgartnerDepartment of Epidemiology and Population Health; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Stephanie D BooneDepartment of Epidemiology and Population Health; James Graham Brown Cancer Center, University of Louisville, Louisville, KY, USA.
Lisa M HinesDepartment of Biology, University of Colorado, Colorado Springs, Colorado Springs, CO, USA.
Roger K WolffDepartment of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
Esther M JohnCancer Prevention Institute of California, Fremont, CA, USA.
Martha L SlatteryDepartment of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
James Graham Brown Foundation · USJohns Hopkins University · USUniversity of Utah · USStanford University · USUniversity of Colorado Colorado Springs · USUniversity of Louisville · US

Funding

CALIFORNIA'S PARTICIPATION IN THE NATIONAL CANCER PREVENTION AND CONTRO PROGRAMU58DP000807 · DP · PUBLIC HEALTH INSTITUTE · PI SNIPES, KURT P · 2007 to 2011
$22.5M
The Johns Hopkins Clinical Research Scholars in Women's Health (BIRCWH)K12HD085845 · NICHD · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2015 to 2023
$4.5M
FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDYR01CA078682 · NCI · UNIVERSITY OF UTAH · PI SLATTERY, MARTHA OR MARTY L · 1999 to 2003
$4.0M
Disparities in Breast Cancer: Development and Survival in Hispanic and NHW WomenR01CA140002 · NCI · UNIVERSITY OF UTAH · PI SLATTERY, MARTHA L · 2009 to 2013
$3.1M
THE 4 CORNERS BREAST AND ENDOMETRIAL CANCER STUDYR01CA078762 · NCI · UNIVERSITY OF NEW MEXICO · PI BAUMGARTNER, KATHY B · 1999 to 2003
$3.0M
FOUR-CORNERS BREAST AND ENDOMETRIAL CANCER STUDYR01CA078802 · NCI · UNIVERSITY OF ARIZONA · PI MARTINEZ, MARIA ELENA · 1999 to 2003
$2.2M
FOUR-CORNERS BREAST CANCER STUDYR01CA078552 · NCI · UNIVERSITY OF COLORADO DENVER · PI BYERS, TIM E · 1999 to 2003
$1.5M
BREAST CANCER RISK FACTORS IN HISPANIC WOMENR01CA063446 · NCI · NORTHERN CALIFORNIA CANCER CENTER · PI JOHN, ESTHER M · 1995 to 1998
–
NCCDPHP CDC HHS U58 DP000807NCI NIH HHS HHSN261201000036CNCI NIH HHS R01 CA063446NCI NIH HHS R01 CA078552NCI NIH HHS R01 CA078682NCI NIH HHS R01 CA078762NCI NIH HHS R01 CA078802NCI NIH HHS R01 CA140002NICHD NIH HHS K12 HD085845
6 · The paper itself

Abstract

backgroundU.S. Hispanic women have high rates of parity, breastfeeding, and obesity. It is unclear whether these reproductive factors are associated with breast cancer (BC) mortality. We examined the associations between breastfeeding, parity, adiposity and BC-specific and overall mortality in Hispanic and non-Hispanic white (NHW) BC cases.

methodsThe study population included 2921 parous women (1477 Hispanics, 1444 NHWs) from the Breast Cancer Health Disparities Study with invasive BC diagnosed between 1995 and 2004. Information on reproductive history and lifestyle factors was collected by in-person interview. Overall and stratified Cox proportional hazard regression models by ethnicity, parity, and body mass index (BMI) at age 30 years were used to calculate hazard ratios (HR) and 95% confidence intervals (CI).

resultsAfter a median follow-up time of 11.2 years, a total of 679 deaths occurred. Pre-diagnostic breastfeeding was associated with a 16% reduction in mortality (HR 0.84; 95% 0.72-0.99) irrespective of ethnicity. Parity significantly modified the association between breastfeeding duration and mortality (p interaction = 0.05), with longer breastfeeding duration associated with lower risk among women who had ≤2 births (p trend = 0.02). Breastfeeding duration was associated with reduced risk of both BC-specific and overall mortality among women with BMI <25 kg/m

conclusionPre-diagnostic breastfeeding was inversely associated with risk of mortality after BC, particularly in women of low parity or normal BMI. These results provide another reason to encourage breastfeeding and weight management among young women.

Indexed as

AdiposityBreast FeedingHispanic or LatinoWhite PeopleAdultAgedAged, 80 and overBreast NeoplasmsCase-Control StudiesCause of DeathFemaleHealthcare DisparitiesHumansMiddle AgedNeoplasm InvasivenessNeoplasm StagingBreast cancer mortalityBreastfeedingHispanic AmericansObesity

Identifiers

PMID27837379
PMCPMC5226868
OpenAlexW2551996536

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.