ArticleSurgery today2017
New-onset diabetes mellitus after living-donor liver transplantation: association with graft synthetic function.
Article in Surgery today, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Impact of New-Onset Diabetes after Transplantation on Cardiovascular Risk and Mortality in Korea: A Nationwide Population-Based Study.Diabetes & metabolism journal · 2025Article
- Safety and efficacy of early corticosteroid withdrawal in liver transplant recipients: A randomized controlled trial.Annals of hepato-biliary-pancreatic surgery · 2024Article
- Clinical characteristics of new-onset diabetes after liver transplantation and outcomes.Annals of gastroenterological surgery · 2024Article
- The need for deepened molecular mechanism exploration in new onset diabetes after transplantation (NODAT).Hepatobiliary surgery and nutrition · 2021Article
- A Time-Based Meta-Analysis on the Incidence of New Onset Diabetes after Liver Transplantation.Journal of clinical medicine · 2021Review
- An Analysis of the Risk Factors for New-Onset Diabetes Mellitus After Liver Transplantation.International journal of general medicine · 2021Article
- New-onset diabetes after adult liver transplantation in the Korean Organ Transplantation Registry (KOTRY) study.Hepatobiliary surgery and nutrition · 2020Article
- Expert consensus on management of metabolic disease in Chinese liver transplant recipients.World journal of gastroenterology · 2020Review
- Post-Liver Transplantation Diabetes Mellitus: A Review of Relevance and Approach to Treatment.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeIt is now known that post-transplant graft function after deceased-donor liver transplantation and living-donor liver transplantation (LDLT) differ; however, there is no report assessing the relationship between graft function and the development of new-onset diabetes mellitus after transplantation (NODAT). We conducted this study to identify the predictive risk factors for NODAT, including graft function after LDLT.
methodsThe subjects of this study were 175 adult recipients who underwent LDLT at Kyoto University Hospital between 2006 and 2010, and survived for more than 3 months (median observation period, 1046 days).
resultsThe 1-, 2-, and 3-year incidences of NODAT after LDLT were 26.1, 32.0, and 33.4%, respectively. Pre-transplant diabetes was associated with poor survival (p = 0.0048), whereas NODAT was not associated with patient survival. In the multivariate analysis, recipient age ≥40, a tacrolimus trough level ≥8 ng/mL 3 months after LDLT, and cholinesterase (ChE) <185 IU/L 3 months after LDLT were the independent risk factors for NODAT.
conclusionsPoor graft synthetic function 3 months after LDLT as well as older age of the recipient and a higher tacrolimus concentration were strongly associated with NODAT development after LDLT.
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