Evidence map›Paper›PMID 27837273›Full record

Trial reportLangenbeck's archives of surgery2017

Chronic pain after inguinal hernia repair with the ONSTEP versus the Lichtenstein technique, results of a double-blinded multicenter randomized clinical trial.

Kristoffer Andresen, Jakob Burcharth, Siv Fonnes, Line Hupfeld, Josephine Philip Rothman, Søren Deigaard, Dorte Winther, Maj-Britt Errebo, Rikke Therkildsen, Dina Hauge and 3 more

2 registry-linked trialsAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Langenbeck's archives of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01753219 nacompletednot on this map

Effect of Suture for Mesh Fixation on Pain and Other Complications in Patients Undergoing Inguinal Hernia Repair: a Double-blind, Randomized Study Comparing the Lichtenstein With the Onstep Technique - the ONLI Trial.

TypeinterventionalSponsorJacob RosenbergRan2013 to 2015Enrolled290ConditionsHernia, Inguinal, Chronic PainArmsOnstep, Lichtenstein
NCT04138329 nacompletednot on this mapstarted 2018, after this paper: background citation

Comparison of Postoperative Inguinal Pain Between the Onstep Technique and the Lichtenstein Technique: A Randomized Controlled Study.

TypeinterventionalSponsorHospital Central "Dr. Ignacio Morones Prieto"Ran2018 to 2019Enrolled40ConditionsChronic Pain Post-ProceduralArmsLichtenstein Technique, Onstep Technique
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Management of chronic pain after hernia repair.Journal of pain research · 2018
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Kristoffer AndresenCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark. kristofferandresen@gmail.com.ORCID http://orcid.org/0000-0002-9820-3580
Jakob BurcharthCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Siv FonnesCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Line HupfeldCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Josephine Philip RothmanCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Søren DeigaardCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Dorte WintherCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Maj-Britt ErreboDepartment of Surgery, Horsens Hospital, Horsens, Denmark.
Rikke TherkildsenDepartment of Surgery, Horsens Hospital, Horsens, Denmark.
Dina HaugeDepartment of Surgery, Bispebjerg Hospital, Bispebjerg, Denmark.
Fritz Søbæk SørensenDagkirurgisk Center Hobro, University Hospital Aalborg, Aalborg, Denmark.
Jesper BjergDepartment of Surgery, Sygehus Lillebælt, Kolding Hospital, Kolding, Denmark.
Jacob RosenbergCenter for Perioperative Optimization, Department of Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKRegional Hospital Horsens · DKAalborg University Hospital · DKBispebjerg Hospital · DKKolding Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe open new simplified totally extraperitoneal (ONSTEP) technique for the repair of inguinal hernia was presented some years ago with promising initial results regarding chronic pain. We conducted a randomized clinical trial investigating the ONSTEP technique versus the Lichtenstein technique with focus on postoperative pain. The aim of this paper was to report the results regarding chronic pain from follow-up at 6 and 12 months for the participants in the ONSTEP versus Lichtenstein trial.

methodsThis study was conducted as a randomized double-blinded clinical trial in male participants with primary unilateral hernias, having surgical repair of their hernia at one of five participating general surgical departments. At surgery, participants were allocated (1:1) to the ONSTEP or the Lichtenstein technique for inguinal hernia repair. Participants were followed up with questionnaires at 6 and 12 months. The primary outcome was the proportion of patients with substantial pain-related impairment of daily functions at 6- and 12-month follow-ups.

resultsFrom April 2013 to May 2014, 290 male patients were included in the study. Regarding follow-up for pain, a total of 259 patients (89%) completed the 6-month follow-up and a total of 236 patients (81%) completed the 12-month follow-up. Regarding pain at the 6- and 12-month follow-ups, no difference was found between groups. Two patients operated with Lichtenstein technique developed severe disabling chronic pain postoperatively, which was not seen in the ONSTEP group.

conclusionThe ONSTEP technique was not superior to the Lichtenstein technique regarding chronic pain following repair of primary inguinal hernias in males.

trial registrationhttps://clinicaltrials.gov NCT01753219.

Indexed as

AdultAgedChronic PainDouble-Blind MethodFollow-Up StudiesHernia, InguinalHerniorrhaphyHumansMaleMiddle AgedPain MeasurementPostoperative PainSurgical MeshTreatment OutcomeChronic painInguinal herniaLichtensteinONSTEPRandomized clinical trial

Identifiers

PMID27837273
OpenAlexW2552925117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.