Evidence map›Paper›PMID 27837208›Full record

Observational studyStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2017

Low-dose external beam radiotherapy for greater trochanteric pain syndrome : Target volume definition and treatment outcome.

Alexander Kaltenborn, Ulrich Martin Carl, Tanja Hinsche, Mirko Nitsche, Robert Michael Hermann

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Trochanteric reduction osteotomy for refractory greater trochanter painful syndrome.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  4. Low-dose radiotherapy for greater trochanteric pain syndrome-a single-centre analysis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  5. Analgesic effects of low-dose radiotherapy in greater trochanteric pain syndrome: results in a clinical series of 155 patients with recurrent or refractory symptoms.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
  6. Non-surgical treatment as the first step to manage peritrochanteric space disorders.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Review
  7. Review
  8. Radiotherapy for painful benign skeletal disorders : Results of a retrospective clinical quality assessment.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
  9. Low-dose radiotherapy: Mayday, mayday. We've been hit!Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
  10. Radiotherapy of epicondylitis humeri : Analysis of 138 elbows treated with a linear accelerator.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
  11. Is low dose radiotherapy an effective treatment for Baker's cyst?Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alexander KaltenbornDepartment of Orthopedic and Trauma Surgery, Federal Armed Forces Hospital Westerstede, Westerstede, Germany.
Ulrich Martin CarlCenter for Radiotherapy and Radiooncology Bremen and Westerstede, Westerstede, Germany.
Tanja HinscheCenter for Radiotherapy and Radiooncology Bremen and Westerstede, Westerstede, Germany.
Mirko NitscheCenter for Radiotherapy and Radiooncology Bremen and Westerstede, Westerstede, Germany.
Robert Michael HermannCenter for Radiotherapy and Radiooncology Bremen and Westerstede, Westerstede, Germany. hermann@strahlentherapie-westerstede.com.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLow-dose external beam radiotherapy (ED-EBRT) is frequently used in the therapy of refractory greater trochanteric pain syndrome (GTPS). As studies reporting treatment results are scarce, we retrospectively analyzed our own patient collectives. PATIENTS AND

methodsIn all, 60 patients (74 hips) received LD-EBRT (6 × 0.5 Gy in 29 hips, 6 × 1 Gy in 45). The endpoint was the patient's reported subjective response to treatment. The influence of different patient and treatment characteristics on treatment outcome was investigated.

resultsAt the end of LD-EBRT, 69% reported partial remission, 4% complete remission, no change 28%. A total of 3 months later (n = 52 hips), the results were 37, 33, and 30% and 18 months after LD-EBRT (n = 47) 21, 51, and 28%. In univariate analysis "inclusion of the total femoral head into the PTV" and "night pain before LD-EBRT" were correlated with symptom remission at the end of LD-EBRT, while "initial increase in pain during LD-EBRT" was significantly associated with treatment failure. In multivariable modeling "initial increase in pain" was identified as a risk factor for treatment failure (p = 0.007; odds ratio [OR] 0.209; 95% confidence interval [CI] 0.048-0.957), while "night pain" was an independent factor for remission (p = 0.038; OR 3.484; 95% CI 1.004-12.6). Three months after LD-EBRT "night pain" and "inclusion of the complete femoral neck circumference into the PTV" were predictive for remission.

conclusionLD-EBRT represents a useful treatment option for patients suffering from GTPS. Three months after therapy two-thirds of the patients reported a partial or complete symptom remission. Especially patients who suffered from nocturnal pain seemed to benefit. Treatment appeared to be more effective when the entire circumference of the femoral neck was encompassed.

Indexed as

Radiotherapy DosageAdultAgedAged, 80 and overArthralgiaFemaleFemurHip JointHumansMaleMiddle AgedPain MeasurementRadiation ExposureSyndromeTreatment OutcomeBursaeBursitis trochantericaGreater trochanteric pain syndromeLow-dose radiotherapyTarget volume definition

Identifiers

PMID27837208
OpenAlexW2565999454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.