ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017
Hyperoxia results in increased aerobic metabolism following acute brain injury.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- The Impact of Short-Term Hyperoxia on Cerebral Metabolism: A Systematic Review and Meta-Analysis.Neurocritical care · 2022Pooled it
- Consensus statement from the 2025 Delphi panel on cerebral microdialysis in critical care.Critical care (London, England) · 2026Review
- Optical and Microdialysis Monitoring of Succinate Prodrug Treatment in a Rotenone-Induced Model of Mitochondrial Dysfunction in Swine.Metabolites · 2026Article
- Cerebral capillary oxygen diffusion: exploring the concept of intracapillary hemoglobin conformational changes.Intensive care medicine experimental · 2024Article
- Investigating the effect of limited spectral information on NIRS-derived changes in hemoglobin and cytochrome-c-oxidase concentration with a diffusion-based model.Biomedical optics express · 2024Article
- Future of neurocritical care: Integrating neurophysics, multimodal monitoring, and machine learning.World journal of critical care medicine · 2024Review
- Nervous System Response to Neurotrauma: A Narrative Review of Cerebrovascular and Cellular Changes After Neurotrauma.Journal of molecular neuroscience : MN · 2024Review
- Review of measurements and imaging of cytochrome-c-oxidase in humans using near-infrared spectroscopy: an update.Biomedical optics express · 2024Review
- The Role of Brain Tissue Oxygenation Monitoring in the Management of Subarachnoid Hemorrhage: A Scoping Review.Neurocritical care · 2023Article
- Cerebral Oxygen Delivery and Consumption in Brain-Injured Patients.Journal of personalized medicine · 2022Review
- Secondary Mechanisms of Neurotrauma: A Closer Look at the Evidence.Diseases (Basel, Switzerland) · 2022Review
- Pulmonary complications and respiratory management in neurocritical care: a narrative review.Chinese medical journal · 2022Review
- The effect of targeted hyperoxemia in a randomized controlled trial employing a long-term resuscitated, model of combined acute subdural hematoma and hemorrhagic shock in swine with coronary artery disease: An exploratory, hypothesis-generating study.Frontiers in medicine · 2022Article
- Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: A narrative review.Frontiers in physiology · 2022Review
- Microcirculation and tissue oxygenation in the head and limbs during hyperbaric oxygen treatment.Diving and hyperbaric medicine · 2021Article
- The Impact of Hyperoxia Treatment on Neurological Outcomes and Mortality in Moderate to Severe Traumatic Brain Injured Patients.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2021Article
- Near Infrared Spectroscopy for High-Temporal Resolution Cerebral Physiome Characterization in TBI: A Narrative Review of Techniques, Applications, and Future Directions.Frontiers in pharmacology · 2021Review
- Oxygen dependency of mitochondrial metabolism indicates outcome of newborn brain injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Observational
- Inhibition of TGF-β-Smad signaling attenuates hyperoxia-induced brain damage in newborn rats.International journal of clinical and experimental pathology · 2019Article
- Hyperoxia enhances slow-wave forebrain states in urethane-anesthetized and naturally sleeping rats.Journal of neurophysiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Acute brain injury is associated with depressed aerobic metabolism. Below a critical mitochondrial pO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.