Evidence map›Paper›PMID 27836982›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2017

Improving Adherence to Smoking Cessation Treatment: Intervention Effects in a Web-Based Randomized Trial.

Amanda L Graham, George D Papandonatos, Sarah Cha, Bahar Erar, Michael S Amato, Nathan K Cobb, Raymond S Niaura, David B Abrams

Erratum issuedOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Nicotine replacement therapy versus control for smoking cessation.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Improving Adherence to Smoking Cessation Treatment: Smoking Outcomes in a Web-based Randomized Trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018
    Trial
  9. Article
  10. A mixed-methods study exploring free nicotine replacement therapy as a strategy to promote tobacco treatment equity at Cancer Center Cessation Initiative sites.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The role of positive emotion in harmful health behavior: Implications for theory and public health campaigns.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Amanda L GrahamSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC.
George D PapandonatosCenter for Statistical Science, Brown University, Providence, RI.
Sarah ChaSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC.
Bahar ErarCenter for Statistical Science, Brown University, Providence, RI.
Michael S AmatoSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC.
Nathan K CobbMeYouHealth, Boston, MA.
Raymond S NiauraSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC.
David B AbramsSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC.
Georgetown University Medical Center · USAmerican Legacy Foundation · USBrown University · USGeorgetown University · US

Funding

Improving Adherence to Web-based Cessation Programs: A Social Network ApproachR01CA155489 · NCI · TRUTH INITIATIVE FOUNDATION · PI GRAHAM, AMANDA L · 2011 to 2015
$2.6M
NCI NIH HHS R01 CA155489
6 · The paper itself

Abstract

backgroundWeb-based smoking cessation interventions can deliver evidence-based treatments to a wide swath of the population, but effectiveness is often limited by insufficient adherence to proven treatment components. This study evaluated the impact of a social network (SN) intervention and free nicotine replacement therapy (NRT) on adherence to evidence-based components of smoking cessation treatment in the context of a Web-based intervention.

methodsA sample of adult U.S. smokers (N = 5290) was recruited via BecomeAnEX.org, a free smoking cessation Web site. Smokers were randomized to one of four arms: (1) an interactive, evidence-based smoking cessation Web site (WEB) alone; (2) WEB in conjunction with an SN intervention designed to integrate participants into the online community (WEB+SN); (3) WEB plus free NRT (WEB+NRT); and (4) the combination of all treatments (WEB+SN+NRT). Adherence outcomes assessed at 3-month follow-up were as follows: Web site utilization metrics, use of skills training components, intratreatment social support, and pharmacotherapy use.

resultsWEB+SN+NRT outperformed all others on Web site utilization metrics, use of practical counseling tools, intratreatment social support, and NRT use. It was the only intervention to promote the sending of private messages and the viewing of community pages over WEB alone. Both social network arms outperformed WEB on most metrics of online community engagement. Both NRT arms showed higher medication use compared to WEB alone.

conclusionsThis study demonstrated the effectiveness of two approaches for improving adherence to evidence-based components of smoking cessation treatment. Integrated approaches to medication provision and social network engagement can enhance adherence to components known to improve cessation. IMPLICATIONS: This study demonstrated that an integrated approach to medication provision and social network integration, when delivered through an online program, can enhance adherence across all three recommended components of an evidence-based smoking cessation program (skills training, social support, and pharmacotherapy use). Nicotine replacement therapy-when provided as part of an integrated program-increases adherence to other program elements, which in turn augment its own therapeutic effects. An explicit focus on approaches to improve treatment adherence is an important first step to identifying leverage points for optimizing intervention effectiveness.

Indexed as

InternetAdultCounselingHumansPatient ComplianceSmoking CessationSocial SupportTobacco Use Cessation DevicesTobacco Use Disorder

Identifiers

PMID27836982
PMCPMC6075377
OpenAlexW2552059484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.