Evidence map›Paper›PMID 27836816›Full record

ArticleJMIR medical informatics2016

Web-based Real-Time Case Finding for the Population Health Management of Patients With Diabetes Mellitus: A Prospective Validation of the Natural Language Processing-Based Algorithm With Statewide Electronic Medical Records.

Le Zheng, Yue Wang, Shiying Hao, Andrew Y Shin, Bo Jin, Anh D Ngo, Medina S Jackson-Browne, Daniel J Feller, Tianyun Fu, Karena Zhang and 13 more

Open access · goldAbstract read
In one paragraph

Article in JMIR medical informatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 2 countries.

Le ZhengTsinghua University, Beijing, China.ORCID http://orcid.org/0000-0003-4744-367X
Yue WangStanford University, Stanford, CA, United States.ORCID http://orcid.org/0000-0002-0981-935X
Shiying HaoStanford University, Stanford, CA, United States.ORCID http://orcid.org/0000-0002-7527-2460
Andrew Y ShinStanford University, Stanford, CA, United States.ORCID http://orcid.org/0000-0001-6713-0609
Bo JinHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0001-9268-7134
Anh D NgoHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0003-0593-8420
Medina S Jackson-BrowneHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0003-0219-0744
Daniel J FellerHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0002-1258-7107
Tianyun FuHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0001-8103-8841
Karena ZhangStanford University, Stanford, CA, United States.ORCID http://orcid.org/0000-0003-4065-2882
Xin ZhouTianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury, Pingjin Hospital Heart Center, Tianjin, China.ORCID http://orcid.org/0000-0003-1395-7103
Chunqing ZhuHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0003-0649-4403
Dorothy DaiHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0001-9778-198X
Yunxian YuSchool of Medicine, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0002-3394-9832
Gang ZhengZhejiang University, Hangzhou, China.ORCID http://orcid.org/0000-0001-5864-2944
Yu-Ming LiTianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury, Pingjin Hospital Heart Center, Tianjin, China.ORCID http://orcid.org/0000-0003-1981-8120
Doff B McElhinneyStanford University, Stanford, CA, United States.ORCID http://orcid.org/0000-0001-7242-0934
Devore S CulverHealthInfoNet, Portland, ME, United States.ORCID http://orcid.org/0000-0001-5826-2079
Shaun T AlfredsHealthInfoNet, Portland, ME, United States.ORCID http://orcid.org/0000-0003-1752-4823
Frank StearnsHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0003-2049-9163
Karl G SylvesterStanford University, Stanford, CA, United States.ORCID http://orcid.org/0000-0002-8559-0155
Eric WidenHBI Solutions Inc, Palo Alto, CA, United States.ORCID http://orcid.org/0000-0002-8999-4659
Xuefeng Bruce LingStanford University, Stanford, CA, United States.ORCID http://orcid.org/0000-0002-5386-3884
Stanford University · USZhejiang University · CNLifenet Health · USPingjin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes case finding based on structured medical records does not fully identify diabetic patients whose medical histories related to diabetes are available in the form of free text. Manual chart reviews have been used but involve high labor costs and long latency.

objectiveThis study developed and tested a Web-based diabetes case finding algorithm using both structured and unstructured electronic medical records (EMRs).

methodsThis study was based on the health information exchange (HIE) EMR database that covers almost all health facilities in the state of Maine, United States. Using narrative clinical notes, a Web-based natural language processing (NLP) case finding algorithm was retrospectively (July 1, 2012, to June 30, 2013) developed with a random subset of HIE-associated facilities, which was then blind tested with the remaining facilities. The NLP-based algorithm was subsequently integrated into the HIE database and validated prospectively (July 1, 2013, to June 30, 2014).

resultsOf the 935,891 patients in the prospective cohort, 64,168 diabetes cases were identified using diagnosis codes alone. Our NLP-based case finding algorithm prospectively found an additional 5756 uncodified cases (5756/64,168, 8.97% increase) with a positive predictive value of .90. Of the 21,720 diabetic patients identified by both methods, 6616 patients (6616/21,720, 30.46%) were identified by the NLP-based algorithm before a diabetes diagnosis was noted in the structured EMR (mean time difference = 48 days).

conclusionsThe online NLP algorithm was effective in identifying uncodified diabetes cases in real time, leading to a significant improvement in diabetes case finding. The successful integration of the NLP-based case finding algorithm into the Maine HIE database indicates a strong potential for application of this novel method to achieve a more complete ascertainment of diagnoses of diabetes mellitus.

Indexed as

data miningdiabetes mellituselectronic medical recordnatural language processing

Identifiers

PMID27836816
PMCPMC5124114
OpenAlexW2555887493

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.