Evidence map›Paper›PMID 27834953›Full record

ArticleCell death and differentiation2017

CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development.

Zhenqing Liu, Jinghui Guo, Yan Wang, Zhihui Weng, Biao Huang, Mei-Kuen Yu, Xiaohu Zhang, Ping Yuan, Hui Zhao, Wai-Yee Chan and 2 more

Abstract read
In one paragraph

Article in Cell death and differentiation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. CFTR mutation is associated with bone differentiation abnormalities in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Revisiting CFTR Interactions: Old Partners and New Players.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhenqing LiuEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Jinghui GuoEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Yan WangEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Zhihui WengEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Biao HuangEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Mei-Kuen YuEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Xiaohu ZhangEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.ORCID 0000-0002-5329-1599
Ping YuanDepartment of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Hui ZhaoKey Laboratory for Regenerative Medicine of the Ministry of Education of China, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Wai-Yee ChanKey Laboratory for Regenerative Medicine of the Ministry of Education of China, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Xiaohua JiangEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.
Hsiao-Chang ChanEpithelial Cell Biology Research Center, The Chinese University of Hong Kong, Hong Kong SAR, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated anion channel capable of conducting both Cl

Indexed as

Animalsbeta CateninCell DifferentiationChloridesColforsinCystic Fibrosis Transmembrane Conductance RegulatorEctodermEmbryonic DevelopmentEmbryo, NonmammalianEndodermFemaleMaleMesodermMiceMice, KnockoutMouse Embryonic Stem Cellsbeta CateninChloridesColforsinCystic Fibrosis Transmembrane Conductance RegulatorTranscription FactorsWnt3A ProteinXenopus Proteins

Identifiers

PMID27834953
PMCPMC5260497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.