ReviewInternational journal of molecular sciences2016
Functional Components of Carob Fruit: Linking the Chemical and Biological Space.
Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Carob (Reviews on recent clinical trials · 2024Pooled it
- Effects of Specific Carob (Nutrients · 2026Trial
- Carob (Nutrients · 2026Review
- Carob Tree: A Review of Traditional Uses, Medicinal Properties, and Future Perspectives in Sustainable Forestry.Life (Basel, Switzerland) · 2026Review
- Maturation-Associated Physiological and Biochemical Transitions in Carob (Ceratonia siliqua L.): Optimizing Harvest Timing Toward Functional Valorization of Fruits.TheScientificWorldJournal · 2026Article
- Evaluation of Commercial Carob Syrups (Foods (Basel, Switzerland) · 2025Article
- Biofortified Calcium Phosphate Nanoparticles Elicit Secondary Metabolite Production in Carob Callus via Biosynthetic Pathway Activation.Plants (Basel, Switzerland) · 2025Article
- Potential of Carob Pulp Powder: Influence of Cultivar on Nutritional Composition, Antioxidant Activity, and Functional Properties.Molecules (Basel, Switzerland) · 2025Article
- Liposomal Encapsulation of Carob (Pharmaceutics · 2025Article
- Effects of grind carob seeds supplementation in the diet of domestic male rabbits, injected with alloxan, on some productive, physiological, and histological traits.Open veterinary journal · 2025Article
- Fortification of Bread with Carob Extract: A Comprehensive Study on Dough Behavior and Product Quality.Foods (Basel, Switzerland) · 2025Article
- Modulation of Antioxidant Capacity, Nutritional Composition, Probiotic Viability After Digestion and Sensory Attributes of Plant-Based Beverages Through Lactic Acid Fermentation.Foods (Basel, Switzerland) · 2025Article
- Study of the effect of dryness and storage on Ceratonia siliqua L. stem extracts and evaluation of their insecticidal activity.Scientific reports · 2025Article
- Investigation of the quality, antimicrobial, and antioxidant effects of commercial carob molasses and determination of phenolic acids by using HPLC.Journal of food science · 2025Article
- Flavonoids as Immunoregulators: Molecular Mechanisms in Regulating Immune Cells and Their Therapeutic Applications in Inflammatory Diseases.Frontiers in immunology · 2025Review
- Extraction, Physicochemical Properties, and Biomedical Applications of Locust Bean Gum: A Comprehensive Review.Mini reviews in medicinal chemistry · 2025Review
- Nutritional value, HPLC-DAD analysis and biological activities of Ceratonia siliqua L. pulp based on in vitro and in silico studies.Scientific reports · 2024Article
- Phytochemical Analysis and Biological Evaluation of Carob Leaf (Molecules (Basel, Switzerland) · 2024Article
- Carob pulp flour as an innovative source of bioactive molecules for the preparation of high-value-added jellies.Heliyon · 2024Article
- Influence of Harvesting Stage on Phytochemical Composition, Antioxidant, and Antidiabetic Activity of ImmatureCurrent issues in molecular biology · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The contribution of natural products to the drug-discovery pipeline has been remarkable since they have served as a rich source for drug development and discovery. Natural products have adapted, during the course of evolution, optimum chemical scaffolds against a wide variety of diseases, including cancer and diabetes. Advances in high-throughput screening assays, assisted by the continuous development on the instrumentation's capabilities and omics, have resulted in charting a large chemical and biological space of drug-like compounds, originating from natural sources. Herein, we attempt to integrate the information on the chemical composition and the associated biological impact of carob fruit in regards to human health. The beneficial and health-promoting effects of carob along with the clinical trials and the drug formulations derived from carob's natural components are presented in this review.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.