Evidence map›Paper›PMID 27834912›Full record

ArticleToxins2016

Curcumin Prevents Aflatoxin B₁ Hepatoxicity by Inhibition of Cytochrome P450 Isozymes in Chick Liver.

Ni-Ya Zhang, Ming Qi, Ling Zhao, Ming-Kun Zhu, Jiao Guo, Jie Liu, Chang-Qin Gu, Shahid Ali Rajput, Christopher Steven Krumm, De-Sheng Qi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 122 citations in OpenAlex.

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  17. Review
  18. Evaluation of Hepatic Detoxification Effects ofAntioxidants (Basel, Switzerland) · 2022
    Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Ni-Ya ZhangDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. zhangniya@mail.hzau.edu.cn.
Ming QiDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. qi_ming1993@126.com.
Ling ZhaoDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. ling930910@126.com.
Ming-Kun ZhuDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. zhumingkun1989@126.com.
Jiao GuoDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. guojiao1991@sina.com.
Jie LiuDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. cherishlj@webmail.hzau.edu.cn.
Chang-Qin GuCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. guchangqin@mail.hzau.edu.cn.
Shahid Ali RajputDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. dr.shahidali@hotmail.com.
Christopher Steven KrummDepartment of Animal Science, Cornell University, Ithaca, NY 14853, USA. csk97@cornell.edu.
De-Sheng QiDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. qds@mail.hzau.edu.cn.
Lv-Hui SunDepartment of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. lvhuisun@mail.hzau.edu.cn.
Huazhong Agricultural University · CNCornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was designed to establish if Curcumin (CM) alleviates Aflatoxin B₁ (AFB₁)-induced hepatotoxic effects and to determine whether alteration of the expression of cytochrome P450 (CYP450) isozymes is involved in the regulation of these effects in chick liver. One-day-old male broilers (

Indexed as

Aflatoxin B1AnimalsCarcinogensChemical and Drug Induced Liver InjuryChickensCurcuminCytochrome P-450 Enzyme InhibitorsCytochrome P-450 Enzyme SystemDNA AdductsIsoenzymesLiverMaleMicrosomes, LiverRNA, MessengerAflatoxin B1CarcinogensCurcuminCytochrome P-450 Enzyme InhibitorsCytochrome P-450 Enzyme SystemDNA AdductsIsoenzymesRNA, MessengerAFBO–DNAaflatoxin B1chickscurcuminCYP450

Identifiers

PMID27834912
PMCPMC5127124
OpenAlexW2556148229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.