Evidence map›Paper›PMID 27834894›Full record

ArticleNutrients2016

Temporal Changes of Human Breast Milk Lipids of Chinese Mothers.

Francesca Giuffrida, Cristina Cruz-Hernandez, Emmanuelle Bertschy, Patric Fontannaz, Isabelle Masserey Elmelegy, Isabelle Tavazzi, Cynthia Marmet, Belén Sanchez-Bridge, Sagar K Thakkar, Carlos Antonio De Castro and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
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  11. Molecules (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Francesca GiuffridaNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. francesca.giuffrida@rdls.nestle.com.
Cristina Cruz-HernandezNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. cristina.cruz-hernandez@rdls.nestle.com.
Emmanuelle BertschyNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. emmanuelle.bertschy@rdls.nestle.com.
Patric FontannazNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. patric.fontannaz@rdls.nestle.com.
Isabelle Masserey ElmelegyNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. isabelle.masserey-elmlegy@rdls.nestle.com.
Isabelle TavazziNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. isabelle.tavazzi@rdls.nestle.com.
Cynthia MarmetNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. cynthia.marmet@rdls.nestle.com.
Belén Sanchez-BridgeNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. belen.sanchez-bridge@rdls.nestle.com.
Sagar K ThakkarNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. sagar.thakkar@rdls.nestle.com.
Carlos Antonio De CastroNestlé Research Center, Nestec Ltd., Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland. carlosantonio.decastro@rdls.nestle.com.
Gerard Vynes-ParesNestlé Research Center Beijing, Building E-F, No. 5 Dijin Road, Haidian District, Beijing 100091, China. gerard.vinyespares@nestle.com.
Yumei ZhangDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing 100191, China. zhangyumei@bjmu.edu.cn.
Peiyu WangDepartment of Social Medicine and Health Education, School of Public Health, Peking University Health Science Center, Beijing 100191, China. wpeiyu@bjmu.edu.cn.
Nestlé (Switzerland) · CHPeking University · CNNestlé (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatty acids (FA), phospholipids (PL), and gangliosides (GD) play a central role in infant growth, immune and inflammatory responses. The aim of this study was to determine FA, PL, and GD compositional changes in human milk (HM) during lactation in a large group of Chinese lactating mothers (540 volunteers) residing in Beijing, Guangzhou, and Suzhou. HM samples were collected after full expression from one breast and while the baby was fed on the other breast. FA were assessed by direct methylation followed by gas chromatography (GC) analysis. PL and GD were extracted using chloroform and methanol. A methodology employing liquid chromatography coupled with an evaporative light scattering detector (ELSD) and with time of flight (TOF) mass spectrometry was used to quantify PL and GD classes in HM, respectively. Saturated FA (SFA), mono-unsaturated FA (MUFA), and PL content decreased during lactation, while polyunsaturated FA (PUFA) and GD content increased. Among different cities, over the lactation time, HM from Beijing showed the highest SFA content, HM from Guangzhou the highest MUFA content and HM from Suzhou the highest

Indexed as

Lipid MetabolismAdultAsian PeopleFemaleHumansLactationLipidsMilk, HumanPostpartum PeriodPregnancyTime FactorsLipidsbreast milkchromatographyFAgangliosidesphospholipids

Identifiers

PMID27834894
PMCPMC5133101
OpenAlexW2552728958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.