Evidence map›Paper›PMID 27834892›Full record

ArticleToxins2016

Towards Engineering Novel PE-Based Immunotoxins by Targeting Them to the Nucleus.

Marta Borowiec, Michal Gorzkiewicz, Joanna Grzesik, Aurelia Walczak-Drzewiecka, Anna Salkowska, Ewelina Rodakowska, Kamil Steczkiewicz, Leszek Rychlewski, Jaroslaw Dastych, Krzysztof Ginalski

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Anti-Salmonella Potential of NewPolish journal of microbiology · 2020
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Comparison of simple and rapid extracting methods of free-tagsJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Marta BorowiecLaboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Zwirki i Wigury 93, Warsaw 02-089, Poland. m.borowiec@cent.uw.edu.pl.
Michal GorzkiewiczLaboratory of Cellular Immunology, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, Lodz 93-232, Poland. mgorzkiewicz@cbm.pan.pl.
Joanna GrzesikLaboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Zwirki i Wigury 93, Warsaw 02-089, Poland. j.grzesik@cent.uw.edu.pl.
Aurelia Walczak-DrzewieckaLaboratory of Cellular Immunology, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, Lodz 93-232, Poland. adrzewiecka@cbm.pan.pl.
Anna SalkowskaLaboratory of Cellular Immunology, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, Lodz 93-232, Poland. asalkowska@cbm.pan.pl.
Ewelina RodakowskaBioInfoBank Institute, Sw. Marcin 80/82 r.355, Poznan 61-809, Poland. ewelinarodakowska@bioinfo.pl.
Kamil SteczkiewiczLaboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Zwirki i Wigury 93, Warsaw 02-089, Poland. k.steczkiewicz@cent.uw.edu.pl.
Leszek RychlewskiBioInfoBank Institute, Sw. Marcin 80/82 r.355, Poznan 61-809, Poland. leszek@bioinfo.pl.
Jaroslaw DastychLaboratory of Cellular Immunology, Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, Lodz 93-232, Poland. jdastych@cbm.pan.pl.
Krzysztof GinalskiLaboratory of Bioinformatics and Systems Biology, Centre of New Technologies, University of Warsaw, Zwirki i Wigury 93, Warsaw 02-089, Poland. kginal@cent.uw.edu.pl.
University of Warsaw · PLBioInfoBank Institute · PLInstitute for Medical Biology · PLPolish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exotoxin A (PE) from

Indexed as

A549 CellsADP Ribose TransferasesBacterial ToxinsCell NucleusCell SurvivalDNA DamageExotoxinsHep G2 CellsHumansImmunotoxinsProtein EngineeringPseudomonas aeruginosa Exotoxin AVirulence FactorsADP Ribose TransferasesBacterial ToxinsExotoxinsImmunotoxinsPseudomonas aeruginosa Exotoxin AVirulence FactorscancercytotoxicityExotoxin Anuclear localization signalnuclease

Identifiers

PMID27834892
PMCPMC5127118
OpenAlexW2555799286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.