Evidence map›Paper›PMID 27834869›Full record

ArticleInternational journal of molecular sciences2016

MicroRNAs 10a and 10b Regulate the Expression of Human Platelet Glycoprotein Ibα for Normal Megakaryopoiesis.

Zuping Zhang, Yali Ran, Tanner S Shaw, Yuandong Peng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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  5. Life (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Zuping ZhangSchool of Basic Medicine, Central South University, Changsha 410013, China. zhangzuping@csu.edu.cn.
Yali RanCardiovascular Research Section, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Ran_yali@163.com.
Tanner S ShawCardiovascular Research Section, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. tshaw@bcm.edu.
Yuandong PengCardiovascular Research Section, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Yuandong@bcm.edu.
Baylor College of Medicine · USCentral South University · CN

Funding

Regulation of Platelet Glycoprotein (GP) Ib-IX Complex Function by Membrane LipidR01HL095676 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI PENG, YUANDONG · 2010 to 2014
$1.5M
NHLBI NIH HHS R01 HL095676
6 · The paper itself

Abstract

MicroRNAs are a class of small non-coding RNAs that bind to the three prime untranslated region (3'-UTR) of target mRNAs. They cause a cleavage or an inhibition of the translation of target mRNAs, thus regulating gene expression. Here, we employed three prediction tools to search for potential miRNA target sites in the 3'-UTR of the human platelet glycoprotein (

Indexed as

3' Untranslated RegionsAnimalsBase SequenceBinding SitesBlood PlateletsCell MembraneCHO CellsCricetulusGene Expression RegulationGenes, ReporterHumansLuciferasesMiceMicroRNAsPlatelet Glycoprotein GPIb-IX ComplexSignal Transduction3' Untranslated Regionsadhesion receptorLuciferasesMicroRNAsMIRN10 microRNA, humanPlatelet Glycoprotein GPIb-IX Complexgene regulationmicroRNAplatelet glycoprotein Ibα

Identifiers

PMID27834869
PMCPMC5133873
OpenAlexW2555295329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.