Evidence map›Paper›PMID 27834844›Full record

ReviewNutrients2016

Nutraceuticals and Their Potential to Treat Duchenne Muscular Dystrophy: Separating the Credible from the Conjecture.

Keryn G Woodman, Chantal A Coles, Shireen R Lamandé, Jason D White

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Targeted Antisense Oligonucleotide-Mediated Skipping of MurineInternational journal of molecular sciences · 2024
    Article
  6. Review
  7. Review
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  9. Review
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  11. CoQ10 augments candesartan protective effect against tourniquet-induced hind limb ischemia-reperfusion: Involvement of non-classical RAS and ROS pathways.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  12. Article
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  15. Review
  16. Review
  17. Natural products, PGC-1Acta pharmaceutica Sinica. B · 2020
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Keryn G WoodmanMurdoch Childrens Research Institute, Royal Children's Hospital, Parkville 3052, Australia. kerynwoodman@icloud.com.
Chantal A ColesMurdoch Childrens Research Institute, Royal Children's Hospital, Parkville 3052, Australia. chantal.coles@mcri.edu.au.
Shireen R LamandéMurdoch Childrens Research Institute, Royal Children's Hospital, Parkville 3052, Australia. shireen.lamande@mcri.edu.au.
Jason D WhiteMurdoch Childrens Research Institute, Royal Children's Hospital, Parkville 3052, Australia. jasondw@unimelb.edu.au.
Royal Children's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, complementary and alternative medicine has become increasingly popular. This trend has not escaped the Duchenne Muscular Dystrophy community with one study showing that 80% of caregivers have provided their Duchenne patients with complementary and alternative medicine in conjunction with their traditional treatments. These statistics are concerning given that many supplements are taken based on purely "anecdotal" evidence. Many nutraceuticals are thought to have anti-inflammatory or anti-oxidant effects. Given that dystrophic pathology is exacerbated by inflammation and oxidative stress these nutraceuticals could have some therapeutic benefit for Duchenne Muscular Dystrophy (DMD). This review gathers and evaluates the peer-reviewed scientific studies that have used nutraceuticals in clinical or pre-clinical trials for DMD and thus separates the credible from the conjecture.

Indexed as

Dietary SupplementsEvidence-Based MedicineAnimalsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsBiomedical ResearchCombined Modality TherapyHumansMuscle, SkeletalMuscular Dystrophy, DuchennePeer Review, ResearchReproducibility of ResultsSeverity of Illness IndexAnti-Inflammatory Agents, Non-SteroidalAntioxidantsBecker muscular dystrophyDuchenne muscular dystrophymdxmusclenutraceuticals

Identifiers

PMID27834844
PMCPMC5133099
OpenAlexW2551958508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.