Evidence map›Paper›PMID 27834807›Full record

ArticleInternational journal of molecular sciences2016

Use of Atomic Force Microscopy to Study the Multi-Modular Interaction of Bacterial Adhesins to Mucins.

A Patrick Gunning, Devon Kavanaugh, Elizabeth Thursby, Sabrina Etzold, Donald A MacKenzie, Nathalie Juge

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Investigation of Changes in Saliva in Radiotherapy-Induced Head Neck Cancer Patients.International journal of environmental research and public health · 2021
    Article
  7. Review
  8. Selection of ImmunobioticMicroorganisms · 2020
    Article
  9. Review
  10. Article
  11. Functional and Genomic Characterization ofFrontiers in microbiology · 2020
    Article
  12. Molecular basis for intestinal mucin recognition by galectin-3 and C-type lectins.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018
    Article
  13. Review
  14. Review
  15. Role ofFrontiers in microbiology · 2018
    Review
  16. Article
  17. Surface Proteins ofFrontiers in microbiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

A Patrick GunningThe Gut Health and Food Safety Institute Strategic Programme, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK. patrick.gunning@ifr.ac.uk.
Devon KavanaughThe Gut Health and Food Safety Institute Strategic Programme, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK. Devon.Kavanaugh@ifr.ac.uk.
Elizabeth ThursbyThe Gut Health and Food Safety Institute Strategic Programme, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK. Elizabeth.Thursby@ifr.ac.uk.
Sabrina EtzoldThe Gut Health and Food Safety Institute Strategic Programme, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK. sabrinaetzold1@gmail.com.
Donald A MacKenzieThe Gut Health and Food Safety Institute Strategic Programme, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK. d.mackenzie91@btinternet.com.
Nathalie JugeThe Gut Health and Food Safety Institute Strategic Programme, Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK. nathalie.juge@ifr.ac.uk.
Quadram Institute · GBNorwich Research Park · GB

Funding

Biotechnology and Biological Sciences Research Council BB/K019554/1Biotechnology and Biological Sciences Research Council BBS/E/F/00044452
6 · The paper itself

Abstract

The mucus layer covering the gastrointestinal (GI) epithelium is critical in selecting and maintaining homeostatic interactions with our gut bacteria. However, the molecular details of these interactions are not well understood. Here, we provide mechanistic insights into the adhesion properties of the canonical mucus-binding protein (MUB), a large multi-repeat cell-surface adhesin found in

Indexed as

Adhesins, BacterialAnimalsBacterial AdhesionCulture Media, ConditionedGalectin 3Gene ExpressionHumansIntestinal MucosaLimosilactobacillus reuteriMicroscopy, Atomic ForceModels, MolecularMucin-3Protein BindingRecombinant ProteinsSwineAdhesins, BacterialCulture Media, ConditionedGalectin 3Mucin-3Recombinant Proteinsatomic force microscopybacterial adhesinsgut microbiotaintestinal mucinLactobacillus reuterimucus binding proteinsingle molecule force spectroscopy

Identifiers

PMID27834807
PMCPMC5133854
OpenAlexW2549980794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.