Evidence map›Paper›PMID 27834802›Full record

ArticleNutrients2016

Prevalence and Characterization of Self-Reported Gluten Sensitivity in The Netherlands.

Tom van Gils, Petula Nijeboer, Catharina E IJssennagger, David S Sanders, Chris J J Mulder, Gerd Bouma

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. Pooled it
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  15. Non-Celiac Gluten Sensitivity: An Update.Medicina (Kaunas, Lithuania) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Tom van GilsCeliac Center Amsterdam, Department Gastroenterology and Hepatology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. t.vangils@vumc.nl.
Petula NijeboerCeliac Center Amsterdam, Department Gastroenterology and Hepatology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. p.nijeboer@vumc.nl.
Catharina E IJssennaggerCeliac Center Amsterdam, Department Gastroenterology and Hepatology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. c.ijssennagger@vumc.nl.
David S SandersAcademic Unit of Gastroenterology, Royal Hallamshire Hospital, Sheffield S10 2JF, UK. David.Sanders@sth.nhs.uk.
Chris J J MulderCeliac Center Amsterdam, Department Gastroenterology and Hepatology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. cjmulder@vumc.nl.
Gerd BoumaCeliac Center Amsterdam, Department Gastroenterology and Hepatology, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. g.bouma@vumc.nl.
Amsterdam UMC Location VUmc · NLRoyal Hallamshire Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA growing number of individuals reports symptoms related to the ingestion of gluten-containing food in the absence of celiac disease. Yet the actual prevalence is not well established.

methodsBetween April 2015 and March 2016, unselected adults visiting marketplaces, dental practices and a university in The Netherlands were asked to complete a modified validated questionnaire for self-reported gluten sensitivity (srGS).

resultsAmong the 785 adults enquired, two had celiac disease. Forty-nine (6.2%) reported symptoms related to the ingestion of gluten-containing food. These individuals were younger, predominantly female and lived more frequently in urban regions compared with the other respondents. Symptoms reported included bloating (74%), abdominal discomfort (49%) and flatulence (47%). A total of 23 (47%) srGS individuals reported having had tried a gluten-free or gluten-restricted diet. Abdominal discomfort related to fermentable oligosaccharide, disaccharide, monosaccharide and polyol (FODMAP)-containing food was more often reported in srGS individuals compared with the other respondents (73.5% vs. 21.7%,

conclusionSelf-reported GS is common in The Netherlands, especially in younger individuals, females and urban regions, although the prevalence was lower than in a comparable recent UK study. It cannot be excluded that FODMAPs are in part responsible for these symptoms.

Indexed as

GlutensAbdominal PainAdultAgedDiet, Gluten-FreeFemaleFermentationFlatulenceFood HypersensitivityHumansMaleMiddle AgedMonosaccharidesNetherlandsOligosaccharidesSelf ReportGlutensMonosaccharidesOligosaccharidesceliac diseaseFODMAPsglutenirritable bowel syndromenon-celiac gluten sensitivitynon-celiac wheat sensitivity

Identifiers

PMID27834802
PMCPMC5133100
OpenAlexW2555144091

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.