ArticleJournal of neonatal-perinatal medicine2016
Alarms, oxygen saturations, and SpO2 averaging time in the NICU.
Article in Journal of neonatal-perinatal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Automated oxygen delivery for preterm infants with respiratory dysfunction.The Cochrane database of systematic reviews · 2023Pooled it
- Evaluation of two SpOBMC pediatrics · 2019Trial
- Crying wolf, alarm safety and management in paediatrics: A scoping review.Journal of advanced nursing · 2025Article
- The Physiological Effects of an Adjusted Alarm Architecture on a Neonatal Intensive Care Unit.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Impact of Alarm Management Training on Adult ICU Nurses' Knowledge, Behaviour, and Fatigue: A Quasi-Experimental Study.Journal of evaluation in clinical practice · 2025Article
- Clinical correlates of a high cardiorespiratory risk score for very low birth weight infants.Pediatric research · 2025Article
- Impact of Pharmacologic Patent Ductus Arteriosus Treatment on Acute Respiratory and Oxygenation Metrics in Very Low Birth Weight Infants.American journal of perinatology · 2025Article
- Tachycardia-Desaturation Episodes in Neonatal Intensive Care Unit Patients with and without Bronchopulmonary Dysplasia.American journal of perinatology · 2025Article
- Article
- A Multiscale Mathematical Model for Fetal Gas Transport and Regulatory Systems During Second Half of Pregnancy.International journal for numerical methods in biomedical engineering · 2025Article
- Caregivers' response to cardiorespiratory events in preterm infants in the NICU - A quantitative overview.Acta paediatrica (Oslo, Norway : 1992) · 2025Observational
- Averaging Times for Pulse Oximeter Measurements - A Review of Manuscripts Published in the Top Five Sleep Medicine Journals.Nature and science of sleep · 2024Review
- Contactless assessment of heart rate in neonates within a clinical environment using imaging photoplethysmography.Frontiers in pediatrics · 2024Article
- Can Intermittent Hypoxemia Help Detect Pulmonary Hypertension in High-risk Preemies?American journal of respiratory and critical care medicine · 2023Article
- Evaluation of the impact of oximeter averaging times on automated FiOFrontiers in pediatrics · 2023Article
- Pulse Oximeter Performance during Rapid Desaturation.Sensors (Basel, Switzerland) · 2022Article
- Modulators Influencing Medication Alert Acceptance: An Explorative Review.Applied clinical informatics · 2022Review
- Intermittent Hypoxemia and Bronchopulmonary Dysplasia: Manifestations of Immature Respiratory Control and the Preterm Lung.American journal of respiratory and critical care medicine · 2021Article
- Nursing and precision predictive analytics monitoring in the acute and intensive care setting: An emerging role for responding to COVID-19 and beyond.International journal of nursing studies advances · 2021Article
- The relationship between intermittent hypoxemia events and neural outcomes in neonates.Experimental neurology · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAlarm overload is a significant concern in the Neonatal Intensive Care Unit (NICU). Selecting a longer oxygen saturation (SpO2) averaging time will reduce the number of alarms but may mask fluctuations in oxygenation.
objectiveCharacterize bedside monitor alarms in the NICU and estimate the impact of longer SpO2 averaging time and alarm delay.
methodsAll bedside monitor alarms were analyzed over a 12-month period in the University of Virginia NICU, using the default averaging time (8 seconds) and SpO2 alarm limits set at 88-95% for infants on supplemental oxygen. In 10 VLBW infants, SpO2 averaging time was lowered to 2 seconds for 24 hours and events of SpO2 out of the target range were estimated with 2-, 8-, or 16-second averaging time, with and without a 15-second alarm delay.
resultsThere were 3,263,590 alarms in the unit over 12 months. Low or high SpO2 alarms constituted 79% of the total, and 55% of these events lasted <15 seconds. In 10 infants we estimated that increasing SpO2 averaging time from 2 to 16 seconds would have led to 53% fewer SpO2 alarms but the mean duration of alarms would have been 2.15-fold longer. Adding a 15-second alarm delay to 2-second SpO2 averaging in this analysis decreased SpO2 alarms by 67%.
conclusionLonger SpO2 averaging times mask the number and severity of events of aberrant oxygenation in preterm infants without decreasing total alarm time. Incorporating an alarm delay with shorter SpO2 averaging times can reduce alarm number and duration, and allow more accurate assessment of oxygenation, which may be important for research into consequences of aberrant oxygenation in this vulnerable population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.