Trial reportMultiple sclerosis (Houndmills, Basingstoke, England)2017
CoDuSe group exercise programme improves balance and reduces falls in people with multiple sclerosis: A multi-centre, randomized, controlled pilot study.
Trial report in Multiple sclerosis (Houndmills, Basingstoke, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Effects of exercise on balance function in people with multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials.Journal of neurology · 2025Pooled it
- Effects of Balance Exercise Interventions on Balance-Related Performance in People With Multiple Sclerosis: A Systematic Review and a Meta-Analysis of Randomized Controlled Trials.Neurorehabilitation and neural repair · 2024Pooled it
- Effects of exercise in people with multiple sclerosis: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- The content and effects of trunk rehabilitation on trunk and upper limb performance in people with multiple sclerosis: a systematic review.European journal of physical and rehabilitation medicine · 2022Pooled it
- Interventions for preventing falls in people with multiple sclerosis.The Cochrane database of systematic reviews · 2019Pooled it
- Group-Based Individualized Comprehensive Core Stability Intervention Improves Balance in Persons With Multiple Sclerosis: A Randomized Controlled Trial.Physical therapy · 2019Trial
- Evaluation of a web-based fall prevention program among people with multiple sclerosis.Multiple sclerosis and related disorders · 2019Trial
- Preventive strategies in neuroimmunology.Neurological research and practice · 2026Review
- Evaluating the Educational Experience of Physiotherapy Students Using the Fitness and Mobility Exercise (FAME) Programme to Learn about Neurological Conditions: An Exploratory Study.Physiotherapy Canada. Physiotherapie Canada · 2024Article
- Predictive Model of Anxiety and Depression Perception in Multiple Sclerosis Patients: Possible Implications for Clinical Treatment.Bioengineering (Basel, Switzerland) · 2024Article
- Results of the MOVE MS Program: A Feasibility Study on Group Exercise for Individuals with Multiple Sclerosis.International journal of environmental research and public health · 2023Article
- Struggling to Keep Up and Have a Good Life: A Qualitative Study of Living With Impaired Balance Control Due to Multiple Sclerosis.Physical therapy · 2023Article
- A highly challenging balance training intervention for people with multiple sclerosis: a feasibility trial.Pilot and feasibility studies · 2023Article
- Physiotherapy for Multiple Sclerosis Patients From Early to Transition Phase: A Scoping Review.Cureus · 2022Article
- Article
- Biofeedback Based Home Balance Training can Improve Balance but Not Gait in People with Multiple Sclerosis.Multiple sclerosis international · 2019Article
- Balance exercise facilitates everyday life for people with multiple sclerosis: A qualitative study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImbalance leading to falls is common in people with multiple sclerosis (PwMS).
objectiveTo evaluate the effects of a balance group exercise programme (CoDuSe) on balance and walking in PwMS (Expanded Disability Status Scale, 4.0-7.5).
methodsA multi-centre, randomized, controlled single-blinded pilot study with random allocation to early or late start of exercise, with the latter group serving as control group for the physical function measures. In total, 14 supervised 60-minute exercise sessions were delivered over 7 weeks. Pretest-posttest analyses were conducted for self-reported near falls and falls in the group starting late. Primary outcome was Berg Balance Scale (BBS). A total of 51 participants were initially enrolled; three were lost to follow-up.
resultsPost-intervention, the exercise group showed statistically significant improvement ( p = 0.015) in BBS and borderline significant improvement in MS Walking Scale ( p = 0.051), both with large effect sizes (3.66; -2.89). No other significant differences were found between groups. In the group starting late, numbers of falls and near falls were statistically significantly reduced after exercise compared to before ( p < 0.001; p < 0.004).
conclusionThis pilot study suggests that the CoDuSe exercise improved balance and reduced perceived walking limitations, compared to no exercise. The intervention reduced falls and near falls frequency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.