Evidence map›Paper›PMID 27834678›Full record

ArticleThe Journal of biological chemistry2016

Receptor Species-dependent Desensitization Controls KCNQ1/KCNE1 K+ Channels as Downstream Effectors of Gq Protein-coupled Receptors.

Marie-Cécile Kienitz, Dilyana Vladimirova, Christian Müller, Lutz Pott, Andreas Rinne

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Angiotensin receptors and αPflugers Archiv : European journal of physiology · 2024
    Article
  3. Signalling of Adrenoceptors: Canonical Pathways and New Paradigms.Handbook of experimental pharmacology · 2024
    Review
  4. Modulation of IJournal of cellular physiology · 2022
    Article
  5. Article
  6. Neurohormonal Regulation of IJournal of the American Heart Association · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marie-Cécile KienitzFrom the Institute of Physiology, Ruhr-University Bochum, Universitätsstrasse 150, D-44780 Bochum, Germany cecile.kienitz@rub.de.
Dilyana VladimirovaFrom the Institute of Physiology, Ruhr-University Bochum, Universitätsstrasse 150, D-44780 Bochum, Germany.
Christian MüllerFrom the Institute of Physiology, Ruhr-University Bochum, Universitätsstrasse 150, D-44780 Bochum, Germany.
Lutz PottFrom the Institute of Physiology, Ruhr-University Bochum, Universitätsstrasse 150, D-44780 Bochum, Germany.
Andreas RinneFrom the Institute of Physiology, Ruhr-University Bochum, Universitätsstrasse 150, D-44780 Bochum, Germany.
Ruhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of G

Indexed as

AnimalsCalciumCalcium SignalingCHO CellsCricetinaeCricetulusGTP-Binding Protein alpha Subunits, Gq-G11HEK293 CellsHumansKCNQ1 Potassium ChannelPhosphatidylinositol 4,5-DiphosphatePotassium Channels, Voltage-GatedProtein Kinase C-deltaReceptor, Muscarinic M1Receptors, Adrenergic, alpha-1CalciumGNAQ protein, humanGTP-Binding Protein alpha Subunits, Gq-G11KCNE1 protein, humanKCNQ1 Potassium ChannelKCNQ1 protein, humanPhosphatidylinositol 4,5-DiphosphatePotassium Channels, Voltage-GatedPRKCD protein, humanProtein Kinase C-deltaReceptor, Muscarinic M1Receptors, Adrenergic, alpha-1adrenergic receptoralpha-adrenergic α1B receptordesensitizationdiacylglycerolfluorescence resonance energy transfer (FRET)IKsion channelK channelKCNQ1muscarinic M1 receptorphosphoinositidePKCreceptor desensitizationsignal transduction

Identifiers

PMID27834678
PMCPMC5159502
OpenAlexW2555488994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.