Evidence map›Paper›PMID 27834391›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2017

Hippocampal GABA

Joseph F Lynch, Patrick Winiecki, T Lee Gilman, Jordan M Adkins, Aaron M Jasnow

Abstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Endocannabinoids inhibit contextual fear memory generalization via hippocampal GABAergic synaptic transmission.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. GABACurrent topics in behavioral neurosciences · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Anterior Cingulate Cortex and Ventral Hippocampal Inputs to the Basolateral Amygdala Selectively Control Generalized Fear.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  14. Review
  15. Cued fear memory generalization increases over time.Learning & memory (Cold Spring Harbor, N.Y.) · 2018
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph F LynchDepartment of Psychological Sciences, Kent State University, Kent, OH, USA.
Patrick WinieckiDepartment of Psychological Sciences, Kent State University, Kent, OH, USA.
T Lee GilmanDepartment of Psychological Sciences, Kent State University, Kent, OH, USA.
Jordan M AdkinsDepartment of Psychological Sciences, Kent State University, Kent, OH, USA.
Aaron M JasnowDepartment of Psychological Sciences, Kent State University, Kent, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many anxiety disorders are characterized by generalization of fear responses to neutral or ambiguous stimuli. Therefore, a comprehensive understanding of the mechanisms contributing to generalized fear is essential for formulating successful treatments for anxiety disorders. Previous research shows that GABA-mediated presynaptic inhibition has a critical role in cued fear generalization, as animals with genetically deleted presynaptic GABA

Indexed as

AnimalsFearGABA-B Receptor AntagonistsGeneralization, PsychologicalGyrus CinguliHippocampusMaleMemory ConsolidationMental RecallMiceMice, Inbred C57BLMice, KnockoutPhosphinic AcidsReceptors, GABA-ACGP 36216GABA-B Receptor AntagonistsGabrb1 protein, mousePhosphinic AcidsReceptors, GABA-A

Identifiers

PMID27834391
PMCPMC5312073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.