Evidence map›Paper›PMID 27834303›Full record

ArticleThe Journal of international medical research2016

Single nucleotide polymorphisms and genotypes of transient receptor potential ion channel and acetylcholine receptor genes from isolated B lymphocytes in myalgic encephalomyelitis/chronic fatigue syndrome patients.

Sonya Marshall-Gradisnik, Samantha Johnston, Anu Chacko, Thao Nguyen, Peter Smith, Donald Staines

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04031716 (Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04031716 naactive not recruitingnot on this mapstarted 2018, after this paper: background citation

Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery

TypeinterventionalSponsorChildren's Hospital Medical Center, CincinnatiRan2018 to 2025Enrolled600ConditionsPain, Postoperative, Excavatum, Pectus, Scoliosis IdiopathicArmsMeditation
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sonya Marshall-Gradisnik1 School of Medical Science, Griffith University, Gold Coast, QLD, Australia.
Samantha Johnston1 School of Medical Science, Griffith University, Gold Coast, QLD, Australia.
Anu Chacko1 School of Medical Science, Griffith University, Gold Coast, QLD, Australia.
Thao Nguyen1 School of Medical Science, Griffith University, Gold Coast, QLD, Australia.
Peter Smith2 The National Centre for Neuroimmunology and Emerging Diseases, Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD Australia.
Donald Staines1 School of Medical Science, Griffith University, Gold Coast, QLD, Australia.
Griffith University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective The pathomechanism of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is unknown; however, a small subgroup of patients has shown muscarinic antibody positivity and reduced symptom presentation following anti-CD20 intervention. Given the important roles of calcium (Ca

Indexed as

Calcium SignalingPolymorphism, Single NucleotideAcetylcholineAdultB-LymphocytesCalciumCase-Control StudiesFatigue Syndrome, ChronicFemaleGene ExpressionGenotypeHumansLymphocyte ActivationMalePrimary Cell CultureProtein IsoformsAcetylcholineCalciumProtein IsoformsReceptors, CholinergicTransient Receptor Potential ChannelsacetylcholineB lymphocyteschronic fatigue syndromemuscarinic receptorsingle nucleotide polymorphismsTransient receptor potential ion channels

Identifiers

PMID27834303
PMCPMC5536760
OpenAlexW2557191831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.