ArticlePsychological medicine2017
Longitudinal associations between late-life depression dimensions and cognitive functioning: a cross-domain latent growth curve analysis.
Article in Psychological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cognitive impairment and depression: Meta-analysis of structural magnetic resonance imaging studies.NeuroImage. Clinical · 2021Pooled it
- Evidence for Structural and Functional Alterations of Frontal-Executive and Corticolimbic Circuits in Late-Life Depression and Relationship to Mild Cognitive Impairment and Dementia: A Systematic Review.Frontiers in neuroscience · 2020Pooled it
- Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis.Psychological medicine · 2019Pooled it
- Trajectories of change in subclinical anxiety and alcohol use during alcohol treatment: A parallel process growth model.Drug and alcohol dependence · 2023Trial
- The association of multi-system health status and its longitudinal changes with cardiovascular disease risk: insights from a secondary analysis of four multinational cohort studies.Journal of global health · 2026Article
- Gender Differences in Co-developmental Trajectories of Internalizing and Externalizing Problems: A 7-Year Longitudinal Study from Ages 3 to 12.Child psychiatry and human development · 2026Article
- Neuropsychiatric and neural correlates of subjective cognitive complaint.Aging clinical and experimental research · 2026Article
- Cognitive Impairment, Dementia and Depression in Older Adults.Journal of clinical medicine · 2026Review
- Accelerated Cognitive Decline in Late Life Depression: The Role of Amyloid-β, Cortico-Limbic Volume, and White Matter Hyperintensities.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Article
- Maximum Likelihood and Bayesian Estimation in Cross-Domain Latent Growth Curve Modeling: The Impact of Reliability, Sample Size, and Missing Data.Structural equation modeling : a multidisciplinary journal · 2026Article
- What Changes First? Mapping the Temporal Ordering of Age-Related Functional Decline across Domains Using 30-Year Longitudinal Data.Gerontology · 2026Article
- Temporal Associations Between Cognitive Impairment and Depression in Older Adults: A Longitudinal Analysis.European journal of investigation in health, psychology and education · 2025Article
- Longitudinal association between sleep quality and fatigue during pregnancy: an observational cohort study.BMC psychiatry · 2025Observational
- Cognitive functioning in older transgender individuals receiving long-term gender-affirming hormone therapy.International journal of transgender health · 2025Article
- Effects of educational attainment on comorbidity of pain and depression in Chinese older adults.Heliyon · 2024Article
- Temporal dynamics of depressive symptoms and cognitive decline in the oldest old: dynamic time warp analysis of the Leiden 85-plus study.Age and ageing · 2024Article
- Erectile Function, Sexual Satisfaction, and Cognitive Decline in Men From Midlife to Older Adulthood.The Gerontologist · 2023Article
- Internet use and depressive symptoms among Chinese older adults: Two sides of internet use.Frontiers in public health · 2023Article
- Challenges in Identifying Individualized Brain Biomarkers of Late Life Depression.Advances in geriatric medicine and research · 2023Article
- Cognitive Function Trajectories and Factors among Chinese Older Adults with Subjective Memory Decline: CHARLS Longitudinal Study Results (2011-2018).International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundCognitive impairment and depression often co-occur in older adults, but it is not clear whether depression is a risk factor for cognitive decline, a psychological reaction to cognitive decline, or whether changes in depressive symptoms correlate with changes in cognitive performance over time. The co-morbid manifestation of depression and cognitive impairment may reflect either a causal effect or a common cause, depending on the specific symptoms experienced and the cognitive functions affected.
methodThe study sample comprised 1506 community-dwelling older adults aged ⩾65 years from the Longitudinal Aging Study Amsterdam (LASA). We conducted cross-domain latent growth curve analyses to examine longitudinal associations between late-life depression dimensions (i.e. depressed affect, positive affect, and somatic symptoms) and specific domains of cognitive functioning (i.e. processing speed, inductive reasoning, immediate recall, and delayed recall).
resultsPoorer delayed recall performance at baseline predicted a steeper increase in depressed affect over time. Steeper decline in processing speed correlated with a steeper increase in somatic symptoms of depression over time.
conclusionsOur findings suggest a prospective association between memory function and depressed affect, whereby older adults may experience an increase in depressed affect in reaction to poor memory function. Somatic symptoms of depression increased concurrently with declining processing speed, which may reflect common neurodegenerative processes. Our findings do not support the hypothesis that depression symptoms may be a risk factor for cognitive decline in the general population. These findings have potential implications for the treatment of late-life depression and for the prognosis of cognitive outcomes.
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