Evidence map›Paper›PMID 27833993›Full record

ArticlePediatric cardiology2017

Galectin-3 in Children with Chronic Heart Failure with Normal and Reduced Ejection Fraction: Relationship to Disease Severity.

Alyaa Amal Kotby, Omneya Ibrahim Youssef, Mohamed Omar Elmaraghy, Osama Salah El Sharkawy

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Novel Biomarkers of Heart Failure in Pediatrics.Children (Basel, Switzerland) · 2022
    Review
  5. A Scoping Review of Galectin-3 as a Biomarker of Cardiovascular Diseases in Pediatric Populations.International journal of environmental research and public health · 2022
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alyaa Amal KotbyPediatrics Department, Faculty of Medicine, Children's Hospital, Ain Shams University, 29dar el ezz, medinet el zahraa, helmeyet el zaytoon, Cairo, 11321, Egypt.
Omneya Ibrahim YoussefPediatrics Department, Faculty of Medicine, Children's Hospital, Ain Shams University, 29dar el ezz, medinet el zahraa, helmeyet el zaytoon, Cairo, 11321, Egypt. ibrahim_omneya@yahoo.com.ORCID http://orcid.org/0000-0002-3366-5661
Mohamed Omar ElmaraghyClinical Pathology Department, Children's Hospital, Ain Shams University, Cairo, Egypt.
Osama Salah El SharkawyPediatrics Department, Faculty of Medicine, Children's Hospital, Ain Shams University, 29dar el ezz, medinet el zahraa, helmeyet el zaytoon, Cairo, 11321, Egypt.
Ain Shams University · EGAin Shams University Hospital · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) progression has not been studied in pediatric patients as well as HF in patients with a normal ejection fraction (HFNEF). We aimed to evaluate galactin-3 in children with HFNEF and reduced ejection fraction (HFREF) and its correlation to disease severity and progression. This cross-sectional study involved 45 chronic HF patients taking G1a (23 HFNEF children) and G1b (22 HFREF children) compared to 45 age- and sex-matched controls (G2) subjected to history taking, Ross functional HF classification, conventional and tissue Doppler echocardiographic systolic and diastolic function assessment (FS%, E/A, S

Indexed as

AdolescentBiomarkersBlood ProteinsChildChild, PreschoolChronic DiseaseCross-Sectional StudiesDisease ProgressionDiureticsEchocardiography, DopplerFemaleGalectin 3GalectinsGlomerular Filtration RateHeart FailureHumansBiomarkersBlood ProteinsDiureticsGalectin 3GalectinsLGALS3 protein, humanSpironolactoneChildrenGalactin-3Heart failureNormal ejection fraction

Identifiers

PMID27833993
OpenAlexW2552901902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.