Evidence map›Paper›PMID 27833854›Full record

ArticleFEBS open bio2016

Human promyelocytic leukemia protein is targeted to distinct subnuclear domains in plant nuclei and colocalizes with nucleolar constituents in a SUMO-dependent manner.

Christian E Lamm, Myriam Scherer, Nina Reuter, Bushra Amin, Thomas Stamminger, Uwe Sonnewald

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christian E LammDivision of Biochemistry Department of Biology Friedrich-Alexander University Erlangen-Nuremberg Germany.
Myriam SchererInstitute for Clinical and Molecular Virology Friedrich-Alexander University Erlangen-Nuremberg Germany.
Nina ReuterInstitute for Clinical and Molecular Virology Friedrich-Alexander University Erlangen-Nuremberg Germany.
Bushra AminDivision of Biochemistry Department of Biology Friedrich-Alexander University Erlangen-Nuremberg Germany; Present address: Department of Chemistry University of Pittsburgh Pittsburgh PA 15260 USA.
Thomas StammingerInstitute for Clinical and Molecular Virology Friedrich-Alexander University Erlangen-Nuremberg Germany.
Uwe SonnewaldDivision of Biochemistry Department of Biology Friedrich-Alexander University Erlangen-Nuremberg Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotic nuclei are subdivided into subnuclear structures. Among the most prominent of these structures are the nucleolus and the PML nuclear bodies (PML-NBs). PML-NBs are spherical multiprotein aggregates of varying size localized in the interchromosomal area. PML-NB formation is dependent on the presence of the promyelocytic leukemia protein (PML) as well as on post-translational modification of core components by covalent attachment of the small ubiquitin-like modifier (SUMO). So far, PML-NBs as well as PML have been described in mammalian cells only, whereas no orthologs are known in the plant kingdom. In order to investigate conserved mechanisms in PML targeting, we expressed human PML (hPML) fused to the GFP in

Indexed as

nuclear bodiesnucleolusplant subnuclear structurespromyelocytic leukemia proteinsmall ubiquitin like modifier

Identifiers

PMID27833854
PMCPMC5095151
OpenAlexW2528968580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.