Evidence map›Paper›PMID 27833666›Full record

ReviewThe EPMA journal2016

The role of testosterone in colorectal carcinoma: pathomechanisms and open questions.

Mohsin H K Roshan, Amos Tambo, Nikolai P Pace

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The EPMA journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mohsin H K RoshanDepartment of Anatomy, Biomedical Sciences Building, University of Malta, Msida, MSD2080 Malta.ORCID 0000-0003-4555-8596
Amos TamboDepartment of Anatomy, Biomedical Sciences Building, University of Malta, Msida, MSD2080 Malta.
Nikolai P PaceDepartment of Anatomy, Biomedical Sciences Building, University of Malta, Msida, MSD2080 Malta.
University of Malta · MT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the fourth commonest type of malignancy after breast, lung and prostate in the USA and accounts for approximately 49,190 deaths annually in USA alone. The 5-year survival rate of CRC has increased over the past decades, in part, due to greater awareness and the widespread implementation of national screening programmes. Recently, a number of studies reported that males have a higher risk of developing CRC due to the action of testosterone. Testosterone is an androgen that is responsible for the development of male secondary sex characteristics and for spermatogenesis. Studies on rats with mutated

Indexed as

Androgen receptor repeatsAndrogensBiomarkerColorectal cancerEstrogen receptorsRisk predictionSertoli cellsTestosterone

Identifiers

PMID27833666
PMCPMC5103431
OpenAlexW2536358996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.