Evidence map›Paper›PMID 27833568›Full record

ArticleFrontiers in psychiatry2016

Mood Instability and Irritability as Core Symptoms of Major Depression: An Exploration Using Rasch Analysis.

Lloyd Balbuena, Rudy Bowen, Marilyn Baetz, Steven Marwaha

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03905876 (Psychological Experience of the End of the Treatment During a Clincal Trial of the Early Phase and Role of the Initial prédispositions), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03905876 nacompletednot on this mapstarted 2019, after this paper: background citation

Psychological Experience of the End of the Treatment During a Clincal Trial of the Early Phase and Role of the Initial prédispositions ( VRAIMENT)

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2019 to 2024Enrolled182ConditionsPsychological Distress, CancerArmsQuestionnaire
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lloyd BalbuenaPsychiatry, University of Saskatchewan , Saskatoon, SK , Canada.
Rudy BowenPsychiatry, University of Saskatchewan , Saskatoon, SK , Canada.
Marilyn BaetzPsychiatry, University of Saskatchewan , Saskatoon, SK , Canada.
Steven MarwahaMental Health and Wellbeing, Warwick Medical School , Coventry , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMood instability (MI) and irritability are related to depression but are not considered core symptoms. Instruments typically code clusters of symptoms that are used to define syndromic depression, but the place of MI and irritability has been under-investigated. Whether they are core symptoms can be examined using Rasch analysis.

methodWe used the UK Psychiatric Morbidity Survey 2000 data (

resultsA subset of five symptoms ( LIMITATIONS: The time frame over which symptoms were experienced varied, and some required recall over the last year. Symptoms other than those examined here might also be core depression symptoms.

conclusionMood instability and irritability are candidate core symptoms of the depressive syndrome and should be part of its clinical assessment.

Indexed as

depressiondiagnosishealth surveysmood instabilitypsychometrics

Identifiers

PMID27833568
PMCPMC5080527

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.