Evidence map›Paper›PMID 27833384›Full record

ArticleWorld journal of gastroenterology2016

Fecal microbiota in pouchitis and ulcerative colitis.

Kai-Yu Li, Jian-Lin Wang, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Pouchitis: pathophysiology and management.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  6. The aetiology of pouchitis in patients with inflammatory bowel disease.Therapeutic advances in gastroenterology · 2024
    Review
  7. Article
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kai-Yu LiKai-Yu Li, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Jian-Lin WangKai-Yu Li, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Jiang-Peng WeiKai-Yu Li, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Sen-Yang GaoKai-Yu Li, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Ying-Ying ZhangKai-Yu Li, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Li-Tian WangKai-Yu Li, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Gang LiuKai-Yu Li, Jiang-Peng Wei, Sen-Yang Gao, Ying-Ying Zhang, Li-Tian Wang, Gang Liu, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the changes in microbiota in feces of patients with ulcerative colitis (UC) and pouchitis using genomic technology.

methodsFecal samples were obtained from UC patients with or without an ileal pouch-anal anastomosis (IPAA) procedure, as well as healthy controls. The touchdown polymerase chain reaction technique was used to amplify the whole V3 region of the 16S rRNA gene, which was transcribed from DNA extracted from fecal samples. Denaturing gradient gel electrophoresis was used to separate the amplicons. The band profiles and similarity indices were analyzed digitally. The predominant microbiota in different groups was confirmed by sequencing the 16S rRNA gene.

resultsMicrobial biodiversity in the healthy controls was significantly higher compared with the UC groups (

conclusionLess diverse fecal microbiota was present in patients with UC and pouchitis. Increased

Indexed as

Case-Control StudiesColitis, UlcerativeFecesHumansPouchitisDisease activity indexIleal pouch-anal anastomosisIntestinal floraPouchitisUlcerative colitis

Identifiers

PMID27833384
PMCPMC5083798
OpenAlexW2543215457

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.