ArticleFunctional ecology2016
Socioecological predictors of immune defences in wild spotted hyenas.
Article in Functional ecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Handling Stress and Sample Storage Are Associated with Weaker Complement-Mediated Bactericidal Ability in Birds but Not Bats.Physiological and biochemical zoology : PBZPooled it
- Total Immunoglobulin G Variation Through the Phenological Cycle of Migrant and Resident Lesser Long-Nosed Bats (Leptonycteris yerbabuenae) in the Drylands of Mexico and Its Relationship With Bacterial Killing-Ability of Plasma.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Mucosal immune responses and intestinal microbiome associations in wild spotted hyenas (Crocuta crocuta).Communications biology · 2025Article
- A global-scale dataset of bat viral detection suggests that pregnancy reduces viral shedding.Proceedings. Biological sciences · 2025Article
- Aggressiveness predicts dominance rank in greylag geese: mirror tests and agonistic interactions.Royal Society open science · 2024Article
- Epigenetic signatures of social status in wild female spotted hyenas (Crocuta crocuta).Communications biology · 2024Article
- Mechanisms of equality and inequality in mammalian societies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Taxonomic, Genomic, and Functional Variation in the Gut Microbiomes of Wild Spotted Hyenas Across 2 Decades of Study.mSystems · 2023Article
- Snap-freezing in the Field: Effect of Sample Holding Time on Performance of Bactericidal Assays.Integrative and comparative biology · 2022Article
- The benefits of being dominant: health correlates of male social rank and age in a marmot.Current zoology · 2022Article
- Noninvasively measured immune responses reflect current parasite infections in a wild carnivore and are linked to longevity.Ecology and evolution · 2021Article
- Linking Human Perceptions and Spotted Hyena Behavior in Urban Areas of Ethiopia.Animals : an open access journal from MDPI · 2020Article
- Juvenile rank acquisition is associated with fitness independent of adult rank.Proceedings. Biological sciences · 2020Article
- Article
- Parasite infections in a social carnivore: Evidence of their fitness consequences and factors modulating infection load.Ecology and evolution · 2019Article
- Social and endocrine correlates of immune function in meerkats: implications for the immunocompetence handicap hypothesis.Royal Society open science · 2018Article
- Social status mediates the fitness costs of infection with canine distemper virus in Serengeti spotted hyenas.Functional ecology · 2018Article
- The Immune and Non-Immune Pathways That Drive Chronic Gastrointestinal Helminth Burdens in the Wild.Frontiers in immunology · 2018Article
- The Intestinal Eukaryotic and Bacterial Biome of Spotted Hyenas: The Impact of Social Status and Age on Diversity and Composition.Frontiers in cellular and infection microbiology · 2017Article
- Socioecological predictors of immune defences in wild spotted hyenas.Functional ecology · 2016Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Social rank can profoundly affect many aspects of mammalian reproduction and stress physiology, but little is known about how immune function is affected by rank and other socio-ecological factors in free-living animals.In this study we examine the effects of sex, social rank, and reproductive status on immune function in long-lived carnivores that are routinely exposed to a plethora of pathogens, yet rarely show signs of disease.Here we show that two types of immune defenses, complement-mediated bacterial killing capacity (BKC) and total IgM, are positively correlated with social rank in wild hyenas, but that a third type, total IgG, does not vary with rank.Female spotted hyenas, which are socially dominant to males in this species, have higher BKC, and higher IgG and IgM concentrations, than do males.Immune defenses are lower in lactating than pregnant females, suggesting the immune defenses may be energetically costly.Serum cortisol and testosterone concentrations are not reliable predictors of basic immune defenses in wild female spotted hyenas.These results suggest that immune defenses are costly and multiple socioecological variables are important determinants of basic immune defenses among wild hyenas. Effects of these variables should be accounted for when attempting to understand disease ecology and immune function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.