ArticleScientific reports2016
An Antarctic molluscan biomineralisation tool-kit.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 21 citations in OpenAlex.
- Diverting the Use of Hand-Operated Tablet Press Machines to Bioassays: A Novel Protocol to Test 'Waste' Insoluble Shell Matrices.Methods and protocols · 2024Article
- Cell type and gene regulatory network approaches in the evolution of spiralian biomineralisation.Briefings in functional genomics · 2023Review
- Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages.Royal Society open science · 2022Article
- Molecular mechanisms of biomineralization in marine invertebrates.The Journal of experimental biology · 2020Review
- Computationally predicted gene regulatory networks in molluscan biomineralization identify extracellular matrix production and ion transportation pathways.Bioinformatics (Oxford, England) · 2020Article
- Molecular modularity and asymmetry of the molluscan mantle revealed by a gene expression atlas.GigaScience · 2018Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Antarctic clam Laternula elliptica lives almost permanently below 0 °C and therefore is a valuable and tractable model to study the mechanisms of biomineralisation in cold water. The present study employed a multidisciplinary approach using histology, immunohistochemistry, electron microscopy, proteomics and gene expression to investigate this process. Thirty seven proteins were identified via proteomic extraction of the nacreous shell layer, including two not previously found in nacre; a novel T-rich Mucin-like protein and a Zinc-dependent metalloprotease. In situ hybridisation of seven candidate biomineralisation genes revealed discrete spatial expression patterns within the mantle tissue, hinting at modular organisation, which is also observed in the mantle tissues of other molluscs. All seven of these biomineralisation candidates displayed evidence of multifunctionality and strong association with vesicles, which are potentially involved in shell secretion in this species.
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